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Judith C. Gasson, Ph.D.

Work Email Address:
jgasson@mednet.ucla.edu Laboratory Address:
Laboratory
700 Tiverton Ave
Factor 11-151
Los Angeles, CA 90095
UNITED STATES

Office Address:
Office
700 Tiverton Ave
Factor 8-684
Los Angeles, CA 90095
UNITED STATES


Work Phone Number:
(310) 825-5268

Web Address:
Judith Gasson's Website
Web-Profile
Jonsson Cancer Center - Information by Judith Gasson
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Judith C. Gasson, Ph.D.
Department / Division Affiliations
Senior Associate Dean for Research, David Geffen School of Medicine at UCLA
Professor, Biological Chemistry, Medicine
Director, Jonsson Comprehensive Cancer Center
Associate Director, CTSI
Co-Director, Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research

Professional Affiliations

1988-1993 Recipient, Leukemia Society of America Scholar Award
1991 Stohlman Memorial Scholar Award, Leukemia Society of America
1991 Inducted into Glover Gallery, Colorado State University
1991 UCLA "Woman of Science"
1985-1988 Recipient, American Cancer Society Junior Faculty Award
1987 Richard F. Dwyer-Eleanor W. Dwyer Fund for Excellence at the Jonsson Comprehensive Cancer Center

Research Interest:

Molecular Physiology of Human Blood Cell Production

Judy Gasson is a professor of Medicine (Hem-Onc) and Biological Chemistry and the director of UCLA?s Jonsson Comprehensive Cancer Center. Her laboratory studies the molecular events that regulate proliferation and differentiation in mouse and human blood cell (hematopoietic) progenitor cells. When these processes become unregulated leukemias and other diseases can result. In the mid-1980s she and her collaborators purified the human Granulocyte-Macrophage Colony-Stimulating-Factor (GM-CSF) and defined many of its biological activities; it was subsequently used to treat patients recovering from bone marrow transplantation. Her current activities are focused upon in vitro model systems that are designed to better understand the interactions between blood cell progenitor cells and the stroma cells necessary for their proliferation and differentiation in the bone marrow.



Biography:

Judith Gasson, Ph.D., became the director of UCLA's Jonsson Comprehensive Cancer Center (JCCC) on Sept. 15, 1995. She is a molecular biologist and is responsible for one of only 40 institutions designated as comprehensive cancer centers by the National Cancer Institute. Gasson earned her doctorate degree in physiology at the University of Colorado in 1979. She did her postdoctoral work at the Salk Institute in La Jolla, CA, studying glucocorticoid hormones, which are made by the adrenal gland in response to stress. In 1983, she left the Salk Institute to join JCCC. Gasson was instrumental in purifying for the first time a hormone-like substance that increases the speed of bone marrow cell reproduction. That substance, called GM-CSF, is used to help prevent infections in cancer patients and to allow those patients to tolerate more chemotherapy and radiation than had previously been possible. For the past fifteen years, Dr. Gasson has been the director of UCLA�s Jonsson Comprehensive Cancer Center (JCCC), among the nation�s top 10, according to U.S. News & World Report. Under her leadership, the JCCC has become a recognized international pioneer in �translating� laboratory discoveries into more effective new therapies for cancer patients everywhere.

Publications:

Hamidi Habib, Gustafason Derek, Pellegrini Matteo, Gasson Judith Identification of novel targets of CSL-dependent Notch signaling in hematopoiesis. PloS one. 2011; 6(5): e20022.
Lynch Maureen R, Gasson Judith C, Paz Helicia Modified ES / OP9 co-culture protocol provides enhanced characterization of hematopoietic progeny. Journal of visualized experiments : JoVE. 2011; 10(52): .
Zhu Min, Saxton Romaine E, Ramos Lillian, Chang David D, Karlan Beth Y, Gasson Judith C, Slamon Dennis J Neutralizing monoclonal antibody to periostin inhibits ovarian tumor growth and metastasis. Molecular cancer therapeutics. 2011; 10(8): 1500-8.
Zhu Min, Fejzo Marlena S, Anderson Lee, Dering Judy, Ginther Charles, Ramos Lillian, Gasson Judith C, Karlan Beth Y, Slamon Dennis J Periostin promotes ovarian cancer angiogenesis and metastasis. Gynecologic oncology. 2010; 119(2): 337-44.
Paz Helicia, Lynch Maureen R, Bogue Clifford W, Gasson Judith C The homeobox gene Hhex regulates the earliest stages of definitive hematopoiesis. Blood. 2010; 116(8): 1254-62.
Zovein Ann C, Turlo Kirsten A, Ponec Ryan M, Lynch Maureen R, Chen Kevin C, Hofmann Jennifer J, Cox Timothy C, Gasson Judith C, Iruela-Arispe M Luisa Vascular remodeling of the vitelline artery initiates extravascular emergence of hematopoietic clusters. Blood. 2010; 116(18): 3435-44.
Zovein Ann C, Hofmann Jennifer J, Lynch Maureen, French Wendy J, Turlo Kirsten A, Yang Yanan, Becker Michael S, Zanetta Lucia, Dejana Elisabetta, Gasson Judith C, Tallquist Michelle D, Iruela-Arispe M Luisa Fate tracing reveals the endothelial origin of hematopoietic stem cells. Cell stem cell. 2008; 3(6): 625-36.
Rubin Ethel, Wu Xinyan, Zhu Tao, Cheung Joyce C Y, Chen Hexin, Lorincz Annaka, Pandita Raj K, Sharma Girdhar G, Ha Hyo Chol, Gasson Judith, Hanakahi Les A, Pandita Tej K, Sukumar Saraswati A role for the HOXB7 homeodomain protein in DNA repair. Cancer research. 2007; 67(4): 1527-35.
Ganapati Uma, Tan Hongying Tina, Lynch Maureen, Dolezal Milana, de Vos Sven, Gasson Judith C Modeling notch signaling in normal and neoplastic hematopoiesis: global gene expression profiling in response to activated notch expression. Stem cells (Dayton, Ohio). 2007; 25(8): 1872-80.
Carlson Anne, Berkowitz Jeanne McAdara, Browning Damaris, Slamon Dennis J, Gasson Judith C, Yates Karen E Expression of c-Fes protein isoforms correlates with differentiation in myeloid leukemias. DNA and cell biology. 2005; 24(5): 311-6.
Carlson Anne, Yates Karen E, Slamon Dennis J, Gasson Judith C Spatial and temporal changes in the subcellular localization of the nuclear protein-tyrosine kinase, c-Fes. DNA and cell biology. 2005; 24(4): 225-34.
Gasson Judith C Why cancer centers matter. Cancer biology & therapy. 2005; 4(4): 493-5.
Yaron Y, McAdara J K, Lynch M, Hughes E, Gasson J C Identification of novel functional regions important for the activity of HOXB7 in mammalian cells. Journal of immunology (Baltimore, Md. : 1950). 2001; 166(8): 5058-67.
Walker L, Carlson A, Tan-Pertel H T, Weinmaster G, Gasson J The notch receptor and its ligands are selectively expressed during hematopoietic development in the mouse. Stem cells (Dayton, Ohio). 2001; 19(6): 543-52.
Villa N, Walker L, Lindsell C E, Gasson J, Iruela-Arispe M L, Weinmaster G Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels. Mechanisms of development. 2001; 108(1-2): 161-4.
Ismail R S, Baldwin R L, Fang J, Browning D, Karlan B Y, Gasson J C, Chang D D Differential gene expression between normal and tumor-derived ovarian epithelial cells. Cancer research. 2000; 60(23): 6744-9.
Tan-Pertel H T, Walker L, Browning D, Miyamoto A, Weinmaster G, Gasson J C Notch signaling enhances survival and alters differentiation of 32D myeloblasts. Journal of immunology (Baltimore, Md. : 1950). 2000; 165(8): 4428-36.
Fuller J F, McAdara J, Yaron Y, Sakaguchi M, Fraser J K, Gasson J C Characterization of HOX gene expression during myelopoiesis: role of HOX A5 in lineage commitment and maturation. Blood. 1999; 93(10): 3391-400.
Crooks G M, Fuller J, Petersen D, Izadi P, Malik P, Pattengale P K, Kohn D B, Gasson J C Constitutive HOXA5 expression inhibits erythropoiesis and increases myelopoiesis from human hematopoietic progenitors. Blood. 1999; 94(2): 519-28.
Walker L, Lynch M, Silverman S, Fraser J, Boulter J, Weinmaster G, Gasson J C The Notch/Jagged pathway inhibits proliferation of human hematopoietic progenitors in vitro. Stem cells (Dayton, Ohio). 1999; 17(3): 162-71.
Doyle S E, Gasson J C Characterization of the role of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit in the activation of JAK2 and STAT5. Blood. 1998; 92(3): 867-76.
Yates K E, Crooks G M, Gasson J C Analysis of Fes kinase activity in myeloid cell growth and differentiation. Stem cells (Dayton, Ohio). 1996; 14(6): 714-24.
Yates K E, Gasson J C Role of c-Fes in normal and neoplastic hematopoiesis. Stem cells (Dayton, Ohio). 1996; 14(1): 117-23.
Ronco L V, Doyle S E, Raines M, Park L S, Gasson J C Conserved amino acids in the human granulocyte-macrophage colony-stimulating factor receptor-binding subunit essential for tyrosine phosphorylation and proliferation. Journal of immunology (Baltimore, Md. : 1950). 1995; 154(7): 3444-53.
Yates K E, Lynch M R, Wong S G, Slamon D J, Gasson J C Human c-FES is a nuclear tyrosine kinase. Oncogene. 1995; 10(6): 1239-42.
Lill M C, Fuller J F, Herzig R, Crooks G M, Gasson J C The role of the homeobox gene, HOX B7, in human myelomonocytic differentiation. Blood. 1995; 85(3): 692-7.
Rosenblatt J D, Miles S, Gasson J C, Prager D Transactivation of cellular genes by human retroviruses. Current topics in microbiology and immunology. 1995; 193(3): 25-49.
Fraser J K, Guerra J J, Nguyen C Y, Indes J E, Gasson J C, Nimer S D Characterization of a cell-type-restricted negative regulatory activity of the human granulocyte-macrophage colony-stimulating factor gene. Molecular and cellular biology. 1994; 14(3): 2213-21.
Fraser J K, Tran S, Nimer S D, Gasson J C Characterization of nuclear factors that bind to a critical positive regulatory element of the human granulocyte-macrophage colony-stimulating factor promoter. Blood. 1994; 84(8): 2523-30.
Sakamoto K M, Fraser J K, Lee H J, Lehman E, Gasson J C Granulocyte-macrophage colony-stimulating factor and interleukin-3 signaling pathways converge on the CREB-binding site in the human egr-1 promoter. Molecular and cellular biology. 1994; 14(9): 5975-85.
Ronco L V, Silverman S L, Wong S G, Slamon D J, Park L S, Gasson J C Identification of conserved amino acids in the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit critical for function. Evidence for formation of a heterodimeric receptor complex prior to ligand binding. The Journal of biological chemistry. 1994; 269(1): 277-83.
Lill M C, Lynch M, Fraser J K, Chung G Y, Schiller G, Glaspy J A, Souza L, Baldwin G C, Gasson J C Production of functional myeloid cells from CD34-selected hematopoietic progenitor cells using a clinically relevant ex vivo expansion system. Stem cells (Dayton, Ohio). 1994; 12(6): 626-37.
Sakamoto K M, Mignacca R C, Gasson J C Signal transduction by granulocyte-macrophage colony-stimulating factor and interleukin-3 receptors. Receptors & channels. 1994; 2(3): 175-81.
Baldwin G C, Benveniste E N, Chung G Y, Gasson J C, Golde D W Identification and characterization of a high-affinity granulocyte-macrophage colony-stimulating factor receptor on primary rat oligodendrocytes. Blood. 1993; 82(11): 3279-82.
Liesveld J L, Rush S, Kempski M C, Turner A R, Brennan J K, Gasson J C, Abboud C N Phenotypic characterization of the human fibrous histiocytoma giant cell tumor (GCT) cell line and its cytokine repertoire. Experimental hematology. 1993; 21(10): 1342-52.
Sakamoto K M, Nimer S D, Rosenblatt J D, Gasson J C HTLV-I and HTLV-II tax trans-activate the human EGR-1 promoter through different cis-acting sequences. Oncogene. 1992; 7(11): 2125-30.
Sakamoto K M, Bardeleben C, Yates K E, Raines M A, Golde D W, Gasson J C 5' upstream sequence and genomic structure of the human primary response gene, EGR-1/TIS8. Oncogene. 1991; 6(5): 867-71.
DiPersio J F, Hedvat C, Ford C F, Golde D W, Gasson J C Characterization of the soluble human granulocyte-macrophage colony-stimulating factor receptor complex. The Journal of biological chemistry. 1991; 266(1): 279-86.
Sakamoto K M, Gasson J C Clinical applications of human granulocyte-macrophage colony-stimulating factor. International journal of cell cloning. 1991; 9(6): 531-41.
Baldwin G C, Golde D W, Widhopf G F, Economou J, Gasson J C Identification and characterization of a low-affinity granulocyte-macrophage colony-stimulating factor receptor on primary and cultured human melanoma cells. Blood. 1991; 78(3): 609-15.
Gasson J C Molecular physiology of granulocyte-macrophage colony-stimulating factor. Blood. 1991; 77(6): 1131-45.
Sakamoto K M, Golde D W, Gasson J C The biology and clinical applications of granulocyte-macrophage colony-stimulating factor. The Journal of pediatrics. 1991; 118(3): S17-20.
Avalos B R, Gasson J C, Hedvat C, Quan S G, Baldwin G C, Weisbart R H, Williams R E, Golde D W, DiPersio J F Human granulocyte colony-stimulating factor: biologic activities and receptor characterization on hematopoietic cells and small cell lung cancer cell lines. Blood. 1990; 75(4): 851-7.
Gasson J C, Fraser J K, Nimer S D Human granulocyte-macrophage colony-stimulating factor (GM-CSF): regulation of expression. Progress in clinical and biological research. 1990; 338(4): 27-41.
Niskanen E, Gasson J C, Egrie J, Wipf K, Golde D W Recombinant human erythroid potentiating activity enhances the effect of erythropoietin in mice. European journal of haematology. 1990; 45(5): 267-70.
Gasson J C, Baldwin G C, Sakamoto K M, DiPersio J F The biology of human granulocyte-macrophage colony-stimulating factor (GM-CSF). Progress in clinical and biological research. 1990; 352(4): 375-84.
Nimer S D, Gasson J C, Hu K, Smalberg I, Williams J L, Chen I S, Rosenblatt J D Activation of the GM-CSF promoter by HTLV-I and -II tax proteins. Oncogene. 1989; 4(6): 671-6.
Weisbart R H, Gasson J C, Golde D W Colony-stimulating factors and host defense. Annals of internal medicine. 1989; 110(4): 297-303.
Kaufman S E, DiPersio J F, Gasson J C Effects of human GM-CSF on neutrophil degranulation in vitro. Experimental hematology. 1989; 17(7): 800-4.
Economou J S, Rhoades K, Essner R, McBride W H, Gasson J C, Morton D L Genetic analysis of the human tumor necrosis factor alpha/cachectin promoter region in a macrophage cell line. The Journal of experimental medicine. 1989; 170(1): 321-6.
Varnum B C, Lim R W, Kujubu D A, Luner S J, Kaufman S E, Greenberger J S, Gasson J C, Herschman H R Granulocyte-macrophage colony-stimulating factor and tetradecanoyl phorbol acetate induce a distinct, restricted subset of primary-response TIS genes in both proliferating and terminally differentiated myeloid cells. Molecular and cellular biology. 1989; 9(8): 3580-3.
Nimer S D, Gates M J, Koeffler H P, Gasson J C Multiple mechanisms control the expression of granulocyte-macrophage colony-stimulating factor by human fibroblasts. Journal of immunology (Baltimore, Md. : 1950). 1989; 143(7): 2374-7.
Baldwin G C, Gasson J C, Kaufman S E, Quan S G, Williams R E, Avalos B R, Gazdar A F, Golde D W, DiPersio J F Nonhematopoietic tumor cells express functional GM-CSF receptors. Blood. 1989; 73(4): 1033-7.
Nimer S D, Morita E A, Martis M J, Wachsman W, Gasson J C Characterization of the human granulocyte-macrophage colony-stimulating factor promoter region by genetic analysis: correlation with DNase I footprinting. Molecular and cellular biology. 1988; 8(5): 1979-84.
DiPersio J, Billing P, Kaufman S, Eghtesady P, Williams R E, Gasson J C Characterization of the human granulocyte-macrophage colony-stimulating factor receptor. The Journal of biological chemistry. 1988; 263(4): 1834-41.
DiPersio J F, Naccache P H, Borgeat P, Gasson J C, Nguyen M H, McColl S R Characterization of the priming effects of human granulocyte-macrophage colony-stimulating factor on human neutrophil leukotriene synthesis. Prostaglandins. 1988; 36(5): 673-91.
Koyanagi Y, O'Brien W A, Zhao J Q, Golde D W, Gasson J C, Chen I S Cytokines alter production of HIV-1 from primary mononuclear phagocytes. Science (New York, N.Y.). 1988; 241(4873): 1673-5.
Fletcher M P, Gasson J C Enhancement of neutrophil function by granulocyte-macrophage colony-stimulating factor involves recruitment of a less responsive subpopulation. Blood. 1988; 71(3): 652-8.
Baldwin G C, Gasson J C, Quan S G, Fleischmann J, Weisbart R, Oette D, Mitsuyasu R T, Golde D W Granulocyte-macrophage colony-stimulating factor enhances neutrophil function in acquired immunodeficiency syndrome patients. Proceedings of the National Academy of Sciences of the United States of America. 1988; 85(8): 2763-6.
Naccache P H, Faucher N, Borgeat P, Gasson J C, DiPersio J F Granulocyte-macrophage colony-stimulating factor modulates the excitation-response coupling sequence in human neutrophils. Journal of immunology (Baltimore, Md. : 1950). 1988; 140(10): 3541-6.
Golde D W, Gasson J C Hormones that stimulate the growth of blood cells. Scientific American. 1988; 259(1): 62-71.
DiPersio J F, Billing P, Williams R, Gasson J C Human granulocyte-macrophage colony-stimulating factor and other cytokines prime human neutrophils for enhanced arachidonic acid release and leukotriene B4 synthesis. Journal of immunology (Baltimore, Md. : 1950). 1988; 140(12): 4315-22.
Niskanen E, Gasson J C, Teates C D, Golde D W In vivo effect of human erythroid-potentiating activity on hematopoiesis in mice. Blood. 1988; 72(2): 806-10.
Avalos B R, Kaufman S E, Tomonaga M, Williams R E, Golde D W, Gasson J C K562 cells produce and respond to human erythroid-potentiating activity. Blood. 1988; 71(6): 1720-5.
Benveniste E N, Tozawa H, Gasson J C, Quan S, Golde D W, Merrill J E Response of human glioblastoma cells to recombinant interleukin-2. Journal of neuroimmunology. 1988; 17(4): 301-14.
Nimer S D, Gasson J C, DiPersio J F The expression and target cell specificity of human granulocyte-macrophage colony-stimulating factor. The Year in immunology. 1988; 3(4): 144-51.
Strife A, Lambek C, Wisniewski D, Gulati S, Gasson J C, Golde D W, Welte K, Gabrilove J L, Clarkson B Activities of four purified growth factors on highly enriched human hematopoietic progenitor cells. Blood. 1987; 69(5): 1508-23.
Weisbart R H, Kwan L, Golde D W, Gasson J C Human GM-CSF primes neutrophils for enhanced oxidative metabolism in response to the major physiological chemoattractants. Blood. 1987; 69(1): 18-21.
Leary A G, Yang Y C, Clark S C, Gasson J C, Golde D W, Ogawa M Recombinant gibbon interleukin 3 supports formation of human multilineage colonies and blast cell colonies in culture: comparison with recombinant human granulocyte-macrophage colony-stimulating factor. Blood. 1987; 70(5): 1343-8.
Owen W F, Rothenberg M E, Silberstein D S, Gasson J C, Stevens R L, Austen K F, Soberman R J Regulation of human eosinophil viability, density, and function by granulocyte/macrophage colony-stimulating factor in the presence of 3T3 fibroblasts. The Journal of experimental medicine. 1987; 166(1): 129-41.
Rosenblatt J D, Gasson J C, Glaspy J, Bhuta S, Aboud M, Chen I S, Golde D W Relationship between human T cell leukemia virus-II and atypical hairy cell leukemia: a serologic study of hairy cell leukemia patients. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 1987; 1(4): 397-401.
Rosenblatt J D, Golde D W, Wachsman W, Giorgi J V, Jacobs A, Schmidt G M, Quan S, Gasson J C, Chen I S A second isolate of HTLV-II associated with atypical hairy-cell leukemia. The New England journal of medicine. 1986; 315(6): 372-7.
Tomonaga M, Golde D W, Gasson J C Biosynthetic (recombinant) human granulocyte-macrophage colony-stimulating factor: effect on normal bone marrow and leukemia cell lines. Blood. 1986; 67(1): 31-6.
Weisbart R H, Golde D W, Gasson J C Biosynthetic human GM-CSF modulates the number and affinity of neutrophil f-Met-Leu-Phe receptors. Journal of immunology (Baltimore, Md. : 1950). 1986; 137(11): 3584-7.
Silberstein D S, Owen W F, Gasson J C, DiPersio J F, Golde D W, Bina J C, Soberman R, Austen K F, David J R Enhancement of human eosinophil cytotoxicity and leukotriene synthesis by biosynthetic (recombinant) granulocyte-macrophage colony-stimulating factor. Journal of immunology (Baltimore, Md. : 1950). 1986; 137(10): 3290-4.
Tomonaga M, Gasson J C, Quan S G, Golde D W Establishment of eosinophilic sublines from human promyelocytic leukemia (HL-60) cells: demonstration of multipotentiality and single-lineage commitment of HL-60 stem cells. Blood. 1986; 67(5): 1433-41.
Le Beau M M, Westbrook C A, Diaz M O, Larson R A, Rowley J D, Gasson J C, Golde D W, Sherr C J Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders. Science (New York, N.Y.). 1986; 231(4741): 984-7.
Fleischmann J, Golde D W, Weisbart R H, Gasson J C Granulocyte-macrophage colony-stimulating factor enhances phagocytosis of bacteria by human neutrophils. Blood. 1986; 68(3): 708-11.
Gasson J C, Kaufman S E, Weisbart R H, Tomonaga M, Golde D W High-affinity binding of granulocyte-macrophage colony-stimulating factor to normal and leukemic human myeloid cells. Proceedings of the National Academy of Sciences of the United States of America. 1986; 83(3): 669-73.
Huebner K, Isobe M, Gasson J C, Golde D W, Croce C M Localization of the gene encoding human erythroid-potentiating activity to chromosome region Xp11.1----Xp11.4. American journal of human genetics. 1986; 38(6): 819-26.
Chan J Y, Slamon D J, Nimer S D, Golde D W, Gasson J C Regulation of expression of human granulocyte/macrophage colony-stimulating factor. Proceedings of the National Academy of Sciences of the United States of America. 1986; 83(22): 8669-73.
Gasson J C, Golde D W, Weisbart R H Biological activities of human granulocyte-macrophage colony-stimulating factor. The Year in immunology. 1985; 184(6009): 118-21.
Gasson J C, Bersch N, Golde D W Characterization of purified human erythroid-potentiating activity. Progress in clinical and biological research. 1985; 184(6009): 95-104.
Weisbart R H, Golde D W, Clark S C, Wong G G, Gasson J C Human granulocyte-macrophage colony-stimulating factor is a neutrophil activator. Nature. 1985; 314(6009): 361-3.
Gasson J C, Golde D W, Kaufman S E, Westbrook C A, Hewick R M, Kaufman R J, Wong G G, Temple P A, Leary A C, Brown E L Molecular characterization and expression of the gene encoding human erythroid-potentiating activity. Nature. 1985; 315(6022): 768-71.
Benveniste E N, Merrill J E, Kaufman S E, Golde D W, Gasson J C Purification and characterization of a human T-lymphocyte-derived glial growth-promoting factor. Proceedings of the National Academy of Sciences of the United States of America. 1985; 82(11): 3930-4.
Slamon D J, Press M F, Souza L M, Murdock D C, Cline M J, Golde D W, Gasson J C, Chen I S Studies of the putative transforming protein of the type I human T-cell leukemia virus. Science (New York, N.Y.). 1985; 228(4706): 1427-30.
Huebner K, Isobe M, Croce C M, Golde D W, Kaufman S E, Gasson J C The human gene encoding GM-CSF is at 5q21-q32, the chromosome region deleted in the 5q- anomaly. Science (New York, N.Y.). 1985; 230(4731): 1282-5.
Chen I S, McLaughlin J, Gasson J C, Clark S C, Golde D W Molecular characterization of genome of a novel human T-cell leukaemia virus. Nature. 1984; 305(5934): 502-5.
Westbrook C A, Gasson J C, Gerber S E, Selsted M E, Golde D W Purification and characterization of human T-lymphocyte-derived erythroid-potentiating activity. The Journal of biological chemistry. 1984; 259(16): 9992-6.
Gasson J C, Weisbart R H, Kaufman S E, Clark S C, Hewick R M, Wong G G, Golde D W Purified human granulocyte-macrophage colony-stimulating factor: direct action on neutrophils. Science (New York, N.Y.). 1984; 226(4680): 1339-42.
Gasson J C, Bourgeois S A new determinant of glucocorticoid sensitivity in lymphoid cell lines. The Journal of cell biology. 1983; 96(2): 409-15.
Gasson J C, Ryden T, Bourgeois S Role of de novo DNA methylation in the glucocorticoid resistance of a T-lymphoid cell line. Nature. 1983; 302(5909): 621-3.
Huet-Minkowski M, Gasson J C, Bourgeois S Induction of glucocorticoid-resistant variants in a murine thymoma line by antitumor drugs. Cancer research. 1981; 41(11 Pt 1): 4540-6.
Gasson J C Forms and activity of high molecular weight adrenocorticotropin in guinea pig. Peptides. 1980; 1(3): 223-9.
Gasson J C Steroidogenic activity of high molecular weight forms of corticotropin. Biochemistry. 1979; 18(19): 4215-24.