Affiliations

Professor In-Residence, Psychiatry and Biobehavioral Sciences, Hatos Center for Neuropharmacology

Member, Brain Research Institute, Cell & Developmental Biology GPB Home Area, Center for Neurodegenerative Disease Studies, Genetics & Genomics GPB Home Area, Neuroscience GPB Home Area

I am interested in the molecular mechanisms that regulate synaptic transmission, and the relationship between changes in neurotransmitter release and neuropsychiatric illnesses such as depression and Parkinson's disease. My laboratory focuses on the function of neurotransmitter transporters, the proteins responsible for transporting neurotransmitters such as dopamine and serotonin across biological membranes. Using a variety of molecular and genetic techniques, we study how neurotransmitter transport is regulated in cultured cells and in the model organism Drosophila, and how changes in transporter function may influence behavior.

David Krantz is Professor in Residence in the Department of Psychiatry and Biobehavioral Sciences at the David Geffen School of Medicine at UCLA. An undergraduate at Brown University, he completed an MD/PhD in the Medical Scientist Training Program at UCLA in 1991, where he performed his dissertation on Drosophila eye development with Larry Zipursky. After a residency in psychiatry at UCLA, he was awarded a Howard Hughes Postdoctoral Fellowship for Physicians to investigate the regulation of vesicular neurotransmitter transporters in Robert Edwards' laboratory at UCSF. He returned to UCLA in 2000, and is currently using Drosophila to study how changes in the function of neurotransmitter transporters may influence synaptic transmission and behavior.

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