Amy Rowat, Ph.D.

Mailing Address:
1125 Terasaki Life Sciences Bldg

Assistant Professor, Integrative Biology and Physiology
Member, Biochemistry, Biophysics & Structural Biology GPB Home Area, Cell & Developmental Biology GPB Home Area, JCCC Cancer and Stem Cell Biology Program Area, Molecular, Cellular & Integrative Physiology GPB Home Area

Amy Rowat, Ph.D., M.Sc., is Assistant Professor in the Department of Integrative Biology & Physiology, UCLA. She is also a member of the UCLA Jonsson Comprehensive Cancer Center, Broad Stem Cell Research Center, Bioengineering Department, Center for Biological Physics, and Business of Science Center. Rowat earned degrees in: B.Sc. Honors Physics; B.A. Asian Studies, French, & Math; M.Sc. Chemistry; and Ph.D. Physics. She was a postdoctoral fellow in the Department of Physics/Division of Engineering & Applied Science, Harvard University as well as Brigham Women’s Hospital. With her background in the physical sciences, her laboratory focuses on the physical properties of cells and nuclei and implications for health and disease. To characterize the mechanical properties of cells and nuclei Dr. Rowat has developed innovative methods to study cells and nuclei, with a focus on fluidic-based technologies for high throughput mechanotyping.


A selected list of publications:

Qi D, Hoelzle DJ, Rowat AC   Probing single cells using flow in microfluidics, Eur. Phys. J, 2012; 204: 85-101.
Lin Yi-Chia, Broedersz Chase P, Rowat Amy C, Wedig Tatjana, Herrmann Harald, Mackintosh Frederick C, Weitz David A   Divalent cations crosslink vimentin intermediate filament tail domains to regulate network mechanics Journal of molecular biology, 2010; 399(4): 637-44.
Agresti Jeremy J, Antipov Eugene, Abate Adam R, Ahn Keunho, Rowat Amy C, Baret Jean-Christophe, Marquez Manuel, Klibanov Alexander M, Griffiths Andrew D, Weitz David A   Ultrahigh-throughput screening in drop-based microfluidics for directed evolution Proceedings of the National Academy of Sciences of the United States of America, 2010; 107(9): 4004-9.
Ebina Wataru, Rowat Amy C, Weitz David A   Electrodes on a budget: Micropatterned electrode fabrication by wet chemical deposition Biomicrofluidics, 2009; 3(3): 34104.
Rafat Marjan, Raad Danielle R, Rowat Amy C, Auguste Debra T   Fabrication of reversibly adhesive fluidic devices using magnetism Lab on a chip, 2009; 9(20): 3016-9.
Rowat Amy C, Bird James C, Agresti Jeremy J, Rando Oliver J, Weitz David A   Tracking lineages of single cells in lines using a microfluidic device Proceedings of the National Academy of Sciences of the United States of America, 2009; 106(43): 18149-54.
Schmitz Christian H J, Rowat Amy C, Köster Sarah, Weitz David A   Dropspots: a picoliter array in a microfluidic device Lab on a chip, 2009; 9(1): 44-9.
Rowat Amy C   Physical properties of the nucleus studied by micropipette aspiration Methods in molecular biology (Clifton, N.J.), 2009; 464(1): 3-12.
Köster Sarah, Angilè Francesco E, Duan Honey, Agresti Jeremy J, Wintner Anton, Schmitz Christian, Rowat Amy C, Merten Christoph A, Pisignano Dario, Griffiths Andrew D, Weitz David A   Drop-based microfluidic devices for encapsulation of single cells Lab on a chip, 2008; 8(7): 1110-5.