Patrick Allard, Ph.D.

Mailing Address:
UCLA Inst for Soc & Gen
BOX 957221, 3320 LSB
Los Angeles , CA 90095

Affiliations
Affiliations
Assistant Professor, Institute for Society and Genetics
Member, CTSI
Biography

Prevention of adverse health effects from environmental exposure is the major focus of the research in the Allard laboratory. Faced with the tens of thousands of untested chemicals released in the environment, we are developing technologies that can rapidly and reliably determine whether these chemicals are safe. We concentrate our efforts on aspects of health that are particularly difficult to examine with current toxicity testing methods such as reproduction, aging and heritable health effects spanning several generations.

The Allard laboratory is part of the UCLA Institute for Society and Genetics. We are also affiliated with the Jonsson Comprehensive Cancer Center, the Institute of the Environment and Sustainability and the Molecular Toxicology Interdepartmental Graduate Program. This gives us a unique angle to examine environmental effects on health from both a molecular and a societal standpoint.

Dr. Patrick Allard, Assistant Professor, leads the laboratory and trained as a Reproductive Biologist, Developmental Biologist and Geneticist at McGill University and Harvard Medical School. The laboratory works closely with the National Institute of Environmental Health Sciences and the Environmental Protection Agency and receives funding from these agencies, the Center for Alternatives to Animal Testing and others.

For more information, please contact: pallard@ucla.edu or visit: http://www.theallardlabatucla.org/

Publications
Malloy Timothy, Zaunbrecher Virginia, Beryt Elizabeth, Judson Richard, Tice Raymond, Allard Patrick, Blake Ann, Cote Ila, Godwin Hilary, Heine Lauren, Kerzic Patrick, Kostal Jakub, Marchant Gary, McPartland Jennifer, Moran Kelly, Nel Andre, Ogunseitan Oladele, Rossi Mark, Thayer Kristina, Tickner Joel, Whittaker Margaret, Zarker Ken Advancing alternatives analysis: The role of predictive toxicology in selecting safer chemical products and processes. Integrated environmental assessment and management. 2017; .
Ramoni Rachel B, Mulvihill John J, Adams David R, Allard Patrick, Ashley Euan A, Bernstein Jonathan A, Gahl William A, Hamid Rizwan, Loscalzo Joseph, McCray Alexa T, Shashi Vandana, Tifft Cynthia J, Tifft Cynthia J, Wise Anastasia L The Undiagnosed Diseases Network: Accelerating Discovery about Health and Disease. American journal of human genetics. 2017; 100(2): 185-192.
Chen Yichang, Shu Le, Qiu Zhiqun, Lee Dong Yeon, Settle Sara J, Que Hee Shane, Telesca Donatello, Yang Xia, Allard Patrick Exposure to the BPA-Substitute Bisphenol S Causes Unique Alterations of Germline Function. PLoS genetics. 2016; 12(7): e1006223.
Lundby Zachary, Camacho Jessica, Allard Patrick Fast Functional Germline and Epigenetic Assays in the Nematode Caenorhabditis elegans. Methods in molecular biology (Clifton, N.J.). 2016; 1473(7): 99-107.
Ferreira Daniel W, Allard Patrick Models of germ cell development and their application for toxicity studies. Environmental and molecular mutagenesis. 2015; 56(8): 637-49.
Allard Patrick Emerging Toxicity Models from Emerging Scientists. Toxicology research. 2015; 4(3): 545-547.
Parodi Daniela A, Sjarif Jasmine, Chen Yichang, Allard Patrick Reproductive toxicity and meiotic dysfunction following exposure to the pesticides Maneb, Diazinon and Fenarimol. Toxicology research. 2015; 4(3): 645-654.
Parodi Daniela A, Damoiseaux Robert, Allard Patrick Comprehensive assessment of germline chemical toxicity using the nematode Caenorhabditis elegans. Journal of visualized experiments : JoVE. 2015; 4(96): 645-654.
Allard Patrick, Kleinstreuer Nicole C, Knudsen Thomas B, Colaiácovo Monica P A C. elegans screening platform for the rapid assessment of chemical disruption of germline function. Environmental health perspectives. 2013; 121(6): 717-24.
Allard Patrick, Colaiácovo Monica P Mechanistic insights into the action of Bisphenol A on the germline using C. elegans. Cell cycle (Georgetown, Tex.). 2011; 10(2): 183-4.
Allard Patrick, Colaiácovo Monica P Bisphenol A impairs the double-strand break repair machinery in the germline and causes chromosome abnormalities. Proceedings of the National Academy of Sciences of the United States of America. 2010; 107(47): 20405-10.
Yang Qin, Allard Patrick, Huang Michael, Zhang Wenling, Clarke Hugh J Proteasomal activity is required to initiate and to sustain translational activation of messenger RNA encoding the stem-loop-binding protein during meiotic maturation in mice. Biology of reproduction. 2010; 82(1): 123-31.
Allard Patrick, Tabin Clifford J Achieving bilateral symmetry during vertebrate limb development. Seminars in cell & developmental biology. 2009; 20(4): 479-84.
Nissim Sahar, Allard Patrick, Bandyopadhyay Amitabha, Harfe Brian D, Tabin Clifford J Characterization of a novel ectodermal signaling center regulating Tbx2 and Shh in the vertebrate limb. Developmental biology. 2007; 304(1): 9-21.
Villaescusa J Carlos, Allard Patrick, Carminati Emanuela, Kontogiannea Maria, Talarico Daniela, Blasi Francesco, Farookhi Riaz, Verrotti Arturo C Clast4, the murine homologue of human eIF4E-Transporter, is highly expressed in developing oocytes and post-translationally modified at meiotic maturation. Gene. 2006; 367(1): 101-9.
Allard Patrick, Yang Qin, Marzluff William F, Clarke Hugh J The stem-loop binding protein regulates translation of histone mRNA during mammalian oogenesis. Developmental biology. 2005; 286(1): 195-206.
Allard Patrick, Champigny Marc J, Skoggard Sarah, Erkmann Judith A, Whitfield Michael L, Marzluff William F, Clarke Hugh J Stem-loop binding protein accumulates during oocyte maturation and is not cell-cycle-regulated in the early mouse embryo. Journal of cell science. 2002; 115(Pt 23): 4577-86.