A selected list of publications:
Watanabe M, Haney JR, Vishlaghi N, Turcios F, Buth JE, Gu W, Collier AJ, Miranda OA, Chen D, Sabri S, Clark AT, Plath K, Christofk HR, Gandal MJ, Novitch BG
TGFβ superfamily signaling regulates the state of human stem cell pluripotency and competency to create telencephalic organoids
bioRxiv,
2019;
875773.
Allison Thomas, Langerman Justin, Sabri Shan, Otero-Garcia Marcos, Lund Andrew, Huang John, Wei Xiaofei, Samarasinghe Ranmal A, Polioudakis Damon, Mody Istvan, Cobos Inma, Novitch Bennett G, Geschwind Daniel H, Plath Kathrin, Lowry William E
Defining the nature of human pluripotent stem cell-derived
interneurons via single-cell analysis
Stem cell reports,
2021; 16(10):
2548-2564.
Samarasinghe Ranmal A, Miranda Osvaldo A, Buth Jessie E, Mitchell Simon, Ferando Isabella, Watanabe Momoko, Allison Thomas F, Kurdian Arinnae, Fotion Namie N, Gandal Michael J, Golshani Peyman, Plath Kathrin, Lowry William E, Parent Jack M, Mody Istvan, Novitch Bennett G
Identification of neural oscillations and epileptiform changes in
human brain organoids
Nature neuroscience,
2021; 24(10):
1488-1500.
Taniguchi-Ikeda Mariko, Koyanagi-Aoi Michiyo, Maruyama Tatsuo, Takaori Toru, Hosoya Akiko, Tezuka Hiroyuki, Nagase Shotaro, Ishihara Takuma, Kadoshima Taisuke, Muguruma Keiko, Ishigaki Keiko, Sakurai Hidetoshi, Mizoguchi Akira, Novitch Bennett G, Toda Tatsushi, Watanabe Momoko, Aoi Takashi
Restoration of the defect in radial glial fiber migration and cortical
plate organization in a brain organoid model of Fukuyama muscular
dystrophy
iScience,
2021; 24(10):
103140.
Sagner Andreas, Gaber Zachary B, Delile Julien, Kong Jennifer H, Rousso David L, Pearson Caroline A, Weicksel Steven E, Melchionda Manuela, Mousavy Gharavy S Neda, Briscoe James, Novitch Bennett G
Olig2 and Hes regulatory dynamics during motor neuron differentiation
revealed by single cell transcriptomics
PLoS biology,
2018; 16(2):
e2003127.
Watanabe Momoko, Buth Jessie E, Vishlaghi Neda, de la Torre-Ubieta Luis, Taxidis Jiannis, Khakh Baljit S, Coppola Giovanni, Pearson Caroline A, Yamauchi Ken, Gong Danyang, Dai Xinghong, Damoiseaux Robert, Aliyari Roghiyh, Liebscher Simone, Schenke-Layland Katja, Caneda Christine, Huang Eric J, Zhang Ye, Cheng Genhong, Geschwind Daniel H, Golshani Peyman, Sun Ren, Novitch Bennett G
Self-Organized Cerebral Organoids with Human-Specific Features Predict
Effective Drugs to Combat Zika Virus Infection
Cell reports,
2017; 21(2):
517-532.
Sangwan Smriti, Zhao Anni, Adams Katrina L, Jayson Christina K, Sawaya Michael R, Guenther Elizabeth L, Pan Albert C, Ngo Jennifer, Moore Destaye M, Soriaga Angela B, Do Thanh D, Goldschmidt Lukasz, Nelson Rebecca, Bowers Michael T, Koehler Carla M, Shaw David E, Novitch Bennett G, Eisenberg David S
Atomic structure of a toxic, oligomeric segment of SOD1 linked to
amyotrophic lateral sclerosis (ALS)
Proceedings of the National Academy of Sciences of the United States of America,
2017; 114(33):
8770-8775.
Varadarajan Supraja G, Kong Jennifer H, Phan Keith D, Kao Tzu-Jen, Panaitof S Carmen, Cardin Julie, Eltzschig Holger, Kania Artur, Novitch Bennett G, Butler Samantha J
Netrin1 Produced by Neural Progenitors, Not Floor Plate Cells, Is
Required for Axon Guidance in the Spinal Cord
Neuron,
2017;
.
Li Chunfeng, Deng Yong-Qiang, Wang Shuo, Ma Feng, Aliyari Roghiyh, Huang Xing-Yao, Zhang Na-Na, Watanabe Momoko, Dong Hao-Long, Liu Ping, Li Xiao-Feng, Ye Qing, Tian Min, Hong Shuai, Fan Junwan, Zhao Hui, Li Lili, Vishlaghi Neda, Buth Jessie E, Au Connie, Liu Ying, Lu Ning, Du Peishuang, Qin F Xiao-Feng, Zhang Bo, Gong Danyang, Dai Xinghong, Sun Ren, Novitch Bennett G, Xu Zhiheng, Qin Cheng-Feng, Cheng Genhong
25-Hydroxycholesterol Protects Host against Zika Virus Infection and
Its Associated Microcephaly in a Mouse Model
Immunity,
2017; 46(3):
446-456.
Huang Chengyang, Su Trent, Xue Yong, Cheng Chen, Lay Fides D, McKee Robin A, Li Meiyang, Vashisht Ajay, Wohlschlegel James, Novitch Bennett G, Plath Kathrin, Kurdistani Siavash K, Carey Michael
Cbx3 maintains lineage specificity during neural differentiation
Genes Dev,
2017; 31(3):
241-246.
Jacob John, Kong Jennifer, Moore Steven, Milton Christopher, Sasai Noriaki, Gonzalez-Quevedo Rosa, Terriente Javier, Imayoshi Itaru, Kageyama Ryoichiro, Kageyama Ryoichoro, Wilkinson David G, Novitch Bennett G, Briscoe James
Retinoid acid specifies neuronal identity through graded expression of Ascl1
Curr Biol,
2013; 23(5):
412-8.
Roy Agnes, Francius Cedric, Rousso David L, Seuntjens Eve, Debruyn Joke, Luxenhofer Georg, Huber Andrea B, Huylebroeck Danny, Novitch Bennett G, Clotman Frederic
Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification
Development,
2012; 139(17):
3109-19.
Kang Peng, Lee Hyun Kyoung, Glasgow Stacey M, Finley Meggie, Donti Tataka, Gaber Zachary B, Graham Brett H, Foster Aaron E, Novitch Bennett G, Gronostajski Richard M, Deneen Benjamin
Sox9 and NFIA coordinate a transcriptional regulatory cascade during
the initiation of gliogenesis
Neuron,
2012; 74(1):
79-94.
Ribes Vanessa, Balaskas Nikolaos, Sasai Noriaki, Cruz Catarina, Dessaud Eric, Cayuso Jordi, Tozer Samuel, Yang Lin Lin, Novitch Ben, Marti Elisa, Briscoe James
Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube
Genes Dev,
2010; 24(11):
1186-200.
Karumbayaram Saravanan, Novitch Bennett G, Patterson Michaela, Umbach Joy A, Richter Laura, Lindgren Anne, Conway Anne E, Clark Amander T, Goldman Steve A, Plath Kathrin, Wiedau-Pazos Martina, Kornblum Harley I, Lowry William E
Directed differentiation of human-induced pluripotent stem cells generates active motor neurons
Stem Cells,
2009; 27(4):
806-11.
Qu Jian, Li Xiaofan, Novitch Bennet G, Zheng Ye, Kohn Matthew, Xie Jian-Ming, Kozinn Spencer, Bronson Roderick, Beg Amer A, Minden Audrey
PAK4 kinase is essential for embryonic viability and for proper neuronal development
Mol Cell Biol,
2003; 23(20):
7122-33.
Sellers W R, Novitch B G, Miyake S, Heith A, Otterson G A, Kaye F J, Lassar A B, Kaelin W G
Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth
Genes Dev,
1998; 12(1):
95-106.