Kyung Hyun Sung
Affiliations
Affiliations
Member, Physics & Biology in Medicine GPB Home Area
Assistant Professor In-Residence, Radiology
Research Interests
My research interest is to develop fast and reliable magnetic resonance imaging (MRI) methods that can provide improved diagnostic contrast and useful information. In particular, my group is currently focused on developing advanced quantitative MRI techniques for early diagnosis, treatment guidance, and therapeutic response assessment for oncologic and cardiac applications. We have developed several novel image reconstruction algorithms and software tools, which improve spatial- and temporal-resolution of MRI and easily facilitate quantitative MRI analysis. Such developments can offer more robust and reproducible measures of biologic markers associated with human cancers and cardiac disease.
Biography:

Dr. Sung received the M.S and Ph.D. degrees in Electrical Engineering from University of Southern California, Los Angeles, in 2005 and 2008, respectively. From 2008 to 2012, he finished his postdoctoral training at Stanford in the Departments of Radiology and joined the University of California, Los Angeles (UCLA) Department of Radiological Sciences in 2012 as an Assistant Professor. His research interest is to develop fast and reliable MRI methods that can provide improved diagnostic contrast and useful information. In particular, his group is currently focused on developing advanced quantitative MRI techniques for early diagnosis, treatment guidance, and therapeutic response assessment for oncologic applications.

Publications

A selected list of publications:

Zhong Xinran, Martin Thomas, Wu Holden H, Nayak Krishna S, Sung Kyunghyun   Prostate DCE-MRI with B1+ correction using an approximated analytical approach Magnetic resonance in medicine, 2018; 79(1): 370-382.
Han Yoseob, Yoo Jaejun, Kim Hak Hee, Shin Hee Jung, Sung Kyunghyun, Ye Jong Chul   Deep learning with domain adaptation for accelerated projection-reconstruction MR Magnetic resonance in medicine, 2018; 79(1): 370-382.
Armstrong Tess, Dregely Isabel, Stemmer Alto, Han Fei, Natsuaki Yutaka, Sung Kyunghyun, Wu Holden H   Free-breathing liver fat quantification using a multiecho 3D stack-of-radial technique Magnetic resonance in medicine, 2018; 79(1): 370-382.
Martin Thomas, Wang Yi, Rashid Shams, Shao Xingfeng, Moeller Steen, Hu Peng, Sung Kyunghyun, Wang Danny Jj   Highly Accelerated SSFP Imaging with Controlled Aliasing in Parallel Imaging and integrated-SSFP (CAIPI-iSSFP) Investigative magnetic resonance imaging, 2017; 21(4): 210-222.
Shao Jiaxin, Liu Dapeng, Sung Kyunghyun, Nguyen Kim-Lien, Hu Peng   Accuracy, precision, and reproducibility of myocardial T1 mapping: A comparison of four T1 estimation algorithms for modified look-locker inversion recovery (MOLLI) Magnetic resonance in medicine, 2017; 78(5): 1746-1756.
Shao Xingfeng, Liu Dapeng, Martin Thomas, Chanlaw Teresa, Devaskar Sherin U, Janzen Carla, Murphy Aisling M, Margolis Daniel, Sung Kyunghyun, Wang Danny J J   Measuring human placental blood flow with multidelay 3D GRASE pseudocontinuous arterial spin labeling at 3T Journal of magnetic resonance imaging : JMRI, 2017; 78(5): 1746-1756.
Saucedo Andres, Lefkimmiatis Stamatios, Rangwala Novena, Kyunghyun Sung Novena   Improved Computational Efficiency of Locally Low Rank MRI Reconstruction Using Iterative Random Patch Adjustments IEEE transactions on medical imaging, 2017; 36(6): 1209-1220.
Felker Ely R, Dregely Isabel, Chung Dong Jin, Sung Kyunghyun, Osuagwu Ferdnand C, Lassman Charles, Sayre James, Wu Holden, Lu David S   Irreversible Electroporation: Defining the MRI Appearance of the Ablation Zone With Histopathologic Correlation in a Porcine Liver Model AJR. American journal of roentgenology, 2017; 208(5): 1141-1146.
Kim Young Kon, Lin Wei-Chan, Sung Kyunghyun, Raman Steven S, Margolis Daniel, Lim Yaeji, Gu Seonhye, Lu David   Reducing Artifacts during Arterial Phase of Gadoxetate Disodium-enhanced MR Imaging: Dilution Method versus Reduced Injection Rate Radiology, 2017; 283(2): 429-437.
Tan Nelly, Lin Wei-Chan, Khoshnoodi Pooria, Asvadi Nazanin H, Yoshida Jeffrey, Margolis Daniel J A, Lu David S K, Wu Holden, Sung Kyung Hyun, Lu David Y, Huang Jaioti, Raman Steven S   In-Bore 3-T MR-guided Transrectal Targeted Prostate Biopsy: Prostate Imaging Reporting and Data System Version 2-based Diagnostic Performance for Detection of Prostate Cancer Radiology, 2017; 283(1): 130-139.
Rangwala Novena A, Dregely Isabel, Wu Holden H, Sung Kyunghyun   Optimization and evaluation of reference region variable flip angle (RR-VFA) B1+ and T Journal of magnetic resonance imaging : JMRI, 2017; 45(3): 751-760.
Dregely Isabel, Margolis Daniel A J, Sung Kyunghyun, Zhou Ziwu, Rangwala Novena, Raman Steven S, Wu Holden H   Rapid quantitative T Magnetic resonance in medicine, 2016; 76(6): 1720-1729.
Yang Xin, Le Minh Hung, Tim Cheng Kwang-Ting, Sung Kyung Hyun, Liu Wenyu   Renal compartment segmentation in DCE-MRI images Medical image analysis, 2016; 32(5): 269-80.
Pan Xinlei, Qian Tianyi, Fernandez-Seara Maria A, Smith Robert X, Li Kuncheng, Ying Kui, Sung Kyunghyun, Wang Danny J J   Quantification of liver perfusion using multidelay pseudocontinuous arterial spin labeling Journal of magnetic resonance imaging : JMRI, 2016; 43(5): 1046-54.
Chin Shy-Chyi, Lin Chien-Yu, Huang Bing-Shen, Tsang Ngan-Ming, Fan Kang-Hsing, Ku Yi-Kang, Hsu Cheng-Lung, Chan Sheng-Chieh, Huang Shiang-Fu, Li Cheng-He, Tseng Hsiao-Jung, Liao Chun-Ta, Liu Ho-Ling, Sung Kyunghyun   Pretreatment Dynamic Contrast-Enhanced MRI Improves Prediction of Early Distant Metastases in Patients With Nasopharyngeal Carcinoma Medicine, 2016; 95(6): e2567.
Chung Dong Jin, Sung Kyunghyun, Osuagwu Ferdnand C, Wu Holden H, Lassman Charles, Lu David S K   Contrast Enhancement Patterns after Irreversible Electroporation: Experimental Study of CT Perfusion Correlated to Histopathology in Normal Porcine Liver Journal of vascular and interventional radiology : JVIR, 2016; 27(1): 104-11.
Srinivasan Subashini, Wu Holden H, Sung Kyunghyun, Margolis Daniel J A, Ennis Daniel B   Fast 3D T2 -weighted imaging using variable flip angle transition into driven equilibrium (3D T2 -TIDE) balanced SSFP for prostate imaging at 3T Magnetic resonance in medicine, 2015; 74(2): 442-51.
Liu Wenyang, Sung Kyunghyun, Ruan Dan   Shape-based motion correction in dynamic contrast-enhanced MRI for quantitative assessment of renal function Medical physics, 2014; 41(12): 122302.
Sung Kyunghyun, Hargreaves Brian A   High-frequency subband compressed sensing MRI using quadruplet sampling Magnetic resonance in medicine, 2013; 70(5): 1306-18.
Sung Kyunghyun, Saranathan Manojkumar, Daniel Bruce L, Hargreaves Brian A   Simultaneous T(1) and B(1) (+) mapping using reference region variable flip angle imaging Magnetic resonance in medicine, 2013; 70(4): 954-61.
Sung Kyunghyun, Daniel Bruce L, Hargreaves Brian A   Location constrained approximate message passing for compressed sensing MRI Magnetic resonance in medicine, 2013; 70(2): 370-81.
Sung Kyunghyun, Daniel Bruce L, Hargreaves Brian A   Transmit B1+ field inhomogeneity and T1 estimation errors in breast DCE-MRI at 3 tesla Journal of magnetic resonance imaging : JMRI, 2013; 38(2): 454-9.
Worters Pauline W, Sung Kyunghyun, Stevens Kathryn J, Koch Kevin M, Hargreaves Brian A   Compressed-sensing multispectral imaging of the postoperative spine Journal of magnetic resonance imaging : JMRI, 2013; 37(1): 243-8.
Hargreaves Brian A, Saranathan Manojkumar, Sung Kyung, Daniel Bruce L   Accelerated breast MRI with compressed sensing European journal of radiology, 2012; 81 Suppl 1(2): S54-5.
Sung Kyunghyun, Lee Hsu-Lei, Hu Houchun H, Nayak Krishna S   Prediction of myocardial signal during CINE balanced SSFP imaging Magma (New York, N.Y.), 2010; 23(2): 85-91.
Jung Hong, Sung Kyunghyun, Nayak Krishna S, Kim Eung Yeop, Ye Jong Chul   k-t FOCUSS: a general compressed sensing framework for high resolution dynamic MRI Magnetic resonance in medicine, 2009; 61(1): 103-16.
Sung Kyunghyun, Nayak Krishna S   Design and use of tailored hard-pulse trains for uniformed saturation of myocardium at 3 Tesla Magnetic resonance in medicine, 2008; 60(4): 997-1002.
Sung Kyunghyun, Nayak Krishna S   B1+ compensation in 3T cardiac imaging using short 2DRF pulses Magnetic resonance in medicine, 2008; 59(3): 441-6.
Sung Kyunghyun, Nayak Krishna S   Measurement and characterization of RF nonuniformity over the heart at 3T using body coil transmission Journal of magnetic resonance imaging : JMRI, 2008; 27(3): 643-8.