Sabeeha Merchant, Ph.D.

Laboratory Address:
Young Hall 5043

Work Address:
Young Hall 5070A

Affiliations
Affiliations
Distinguished Professor, Biochemistry, Molecular Biology
Research Interests
Plants require CO2, water, sunlight and a few minerals for growth and survival. Carbon contributes to biomass and sunlight the energy. The mineral requirement includes elements, found only at trace levels, like Fe, Zn, Cu and Mn, that enable the catalysis of an amazing repertoire of reactions, especially in the photosynthetic apparatus where biology’s most powerful oxidants and reductants are found. This structure is rich in metalloproteins and contributes to the high metal quota of some photosynthetic cells. Environmental factors can limit the availability of metals, especially Fe, but also Cu and Zn, and this naturally impacts photosynthetic performance and hence global primary productivity. The Merchant group has discovered mechanisms used by photosynthetic organisms to optimize performance in face of changing metal supply, especially limitation. Reduce, reuse and recycle! For instance, the Cu quota is dramatically reduced (to less than 5% relative to a Cu replete situation) by replacement of the copper-protein plastocyanin in photosynthesis with a functionally equivalent heme-containing cytochrome. This occurs through the action of a copper sensor and a transcription factor that recognizes copper response elements associated with the CYC6 gene. In parallel, plastocyanin is degraded, releasing the Cu cofactor, which is re-used for the biosynthesis of respiratory chain cytochrome oxidase. Similarly, Fe is recycled by degradation of ferredoxin to support the synthesis of an Fe-containing superoxide dismutase. The risk associated with the dynamics of metal ion metabolism is reduced by intracellular storage of these metals in a lysosome-related organelle. In ongoing work, the Merchant laboratory uses elemental and protein mass spectrometry in combination with live cell imaging of metal sensors and classical genetics to discover and dissect the biochemistry of the metal storing compartment.

The Merchant group is also taking advantage of genome-sequencing based approaches for discovery of new components and functions related to photosynthesis and chloroplast biology. The group has amassed the largest collection of RNA-Seq data for Chlamydomonas and are presently creating co-expression networks with a view to deducing the functions of the many unannotated and uncharacterized proteins encoded in the algal genome. This work complements the prior and ongoing phylogenomics approaches for predicting functions for uncharacterized proteins in the plant lineage. Genomes of extremophile algae, isolated from acid mines or from the Svalbard archipelago, are being sequenced and assembled, with a view to discovering mechanisms for light sensing, photoprotection, CO2 concentration and pyrenoid structure and function.

Rising concerns about energy security and the environmental impacts of fossil fuel dependence has created a resurgence in interest in alternative fuel sources. "Biodiesel Fuel" by Prof. Suzanne Paulson of the UCLA Department of Atmospheric & Oceanic Sciences and the Institute of the Environment examines the different types of biodiesel fuel source material, the resources needed to produce this fuel, climate impacts and future applications. The Merchant laboratory has used systems biology approaches, including metabolomics, proteomics and transcriptomics, to deduce the metabolic pathways and regulatory factors that promote the synthesis of triglycerides in Chlamydomonas.

Biography:

Dr. Merchant received her B.S. and Ph.D. from the University of Wisconsin-Madison. She was a Post-doctoral Scholar at Harvard University.

Publications
Xue Yong, Schmollinger Stefan, Attar Narsis, Campos Oscar, Vogelauer Maria, Carey Michael F, Merchant Sabeeha S, Kurdistani Siavash K Endoplasmic reticulum-mitochondria junction is required for iron homeostasis. The Journal of biological chemistry. 2017; 39: 88-96.
Blaby-Haas Crysten E, Merchant Sabeeha S Regulating cellular trace metal economy in algae. Current opinion in plant biology. 2017; 39: 88-96.
Kumar Dhivya, Strenkert Daniela, Patel-King Ramila S, Leonard Michael T, Merchant Sabeeha S, Mains Richard E, King Stephen M, Eipper Betty A A bioactive peptide amidating enzyme is required for ciliogenesis. eLife. 2017; 6(21): E4296-E4305.
Wells Mark L, Potin Philippe, Craigie James S, Raven John A, Merchant Sabeeha S, Helliwell Katherine E, Smith Alison G, Camire Mary Ellen, Brawley Susan H Algae as nutritional and functional food sources: revisiting our understanding. Journal of applied phycology. 2017; 29(2): 949-982.
Roth Melissa S, Cokus Shawn J, Gallaher Sean D, Walter Andreas, Lopez David, Erickson Erika, Endelman Benjamin, Westcott Daniel, Larabell Carolyn A, Merchant Sabeeha S, Pellegrini Matteo, Niyogi Krishna K Chromosome-level genome assembly and transcriptome of the green alga Chromochloris zofingiensis illuminates astaxanthin production. Proceedings of the National Academy of Sciences of the United States of America. 2017; 114(21): E4296-E4305.
Merchant Sabeeha, Eckardt Nancy A The Plant Cell Begins Opt-in Publishing of Peer Review Reports. The Plant cell. 2016; 28(10): 2343.
Strenkert Daniela, Limso Clariss Ann, Fatihi Abdelhak, Schmollinger Stefan, Basset Gilles J, Merchant Sabeeha S Genetically programmed changes in photosynthetic cofactor metabolism in copper deficient Chlamydomonas. The Journal of biological chemistry. 2016; .
Blaby-Haas Crysten E, Castruita Madeli, Fitz-Gibbon Sorel T, Kropat Janette, Merchant Sabeeha S Ni induces the CRR1-dependent regulon revealing overlap and distinction between hypoxia and Cu deficiency responses in Chlamydomonas reinhardtii. Metallomics : integrated biometal science. 2016; 8(7): 679-91.
Reyes Vincent C, Spitzmiller Melissa R, Hong-Hermesdorf Anne, Kropat Janette, Damoiseaux Robert D, Merchant Sabeeha S, Mahendra Shaily Copper status of exposed microorganisms influences susceptibility to metallic nanoparticles. Environmental toxicology and chemistry / SETAC. 2016; 35(5): 1148-58.
Traller Jesse C, Cokus Shawn J, Lopez David A, Gaidarenko Olga, Smith Sarah R, McCrow John P, Gallaher Sean D, Podell Sheila, Thompson Michael, Cook Orna, Morselli Marco, Jaroszewicz Artur, Allen Eric E, Allen Andrew E, Merchant Sabeeha S, Pellegrini Matteo, Hildebrand Mark Genome and methylome of the oleaginous diatom Cyclotella cryptica reveal genetic flexibility toward a high lipid phenotype. Biotechnology for biofuels. 2016; 9(2): 258.
Kumar Dhivya, Blaby-Haas Crysten E, Merchant Sabeeha S, Mains Richard E, King Stephen M, Eipper Betty A Early eukaryotic origins for cilia-associated bioactive peptide-amidating activity. Journal of cell science. 2016; 129(5): 943-56.
Anderson Alexander, Laohavisit Anuphon, Blaby Ian K, Bombelli Paolo, Howe Christopher J, Merchant Sabeeha S, Davies Julia M, Smith Alison G Exploiting algal NADPH oxidase for biophotovoltaic energy. Plant biotechnology journal. 2016; 14(1): 22-8.
Yang Wenqiang, Wittkopp Tyler M, Li Xiaobo, Warakanont Jaruswan, Dubini Alexandra, Catalanotti Claudia, Kim Rick G, Nowack Eva C M, Mackinder Luke C M, Aksoy Munevver, Page Mark Dudley, D'Adamo Sarah, Saroussi Shai, Heinnickel Mark, Johnson Xenie, Richaud Pierre, Alric Jean, Boehm Marko, Jonikas Martin C, Benning Christoph, Merchant Sabeeha S, Posewitz Matthew C, Grossman Arthur R Critical role of Chlamydomonas reinhardtii ferredoxin-5 in maintaining membrane structure and dark metabolism. Proceedings of the National Academy of Sciences of the United States of America. 2015; 112(48): 14978-83.
Lopez David, Hamaji Takashi, Kropat Janette, De Hoff Peter, Morselli Marco, Rubbi Liudmilla, Fitz-Gibbon Sorel, Gallaher Sean D, Merchant Sabeeha S, Umen James, Pellegrini Matteo Dynamic Changes in the Transcriptome and Methylome of Chlamydomonas reinhardtii throughout Its Life Cycle. Plant physiology. 2015; 169(4): 2730-43.
Blaby Ian K, Blaby-Haas Crysten E, Pérez-Pérez María Esther, Schmollinger Stefan, Fitz-Gibbon Sorel, Lemaire Stéphane D, Merchant Sabeeha S Genome-wide analysis on Chlamydomonas reinhardtii reveals the impact of hydrogen peroxide on protein stress responses and overlap with other stress transcriptomes. The Plant journal : for cell and molecular biology. 2015; 84(5): 974-88.
Barahimipour Rouhollah, Strenkert Daniela, Neupert Juliane, Schroda Michael, Merchant Sabeeha S, Bock Ralph Dissecting the contributions of GC content and codon usage to gene expression in the model alga Chlamydomonas reinhardtii. The Plant journal : for cell and molecular biology. 2015; 84(4): 704-17.
Zones James Matt, Blaby Ian K, Merchant Sabeeha S, Umen James G High-Resolution Profiling of a Synchronized Diurnal Transcriptome from Chlamydomonas reinhardtii Reveals Continuous Cell and Metabolic Differentiation. The Plant cell. 2015; 27(10): 2743-69.
Pérez-Martín Marta, Blaby-Haas Crysten E, Pérez-Pérez María Esther, Andrés-Garrido Ascensión, Blaby Ian K, Merchant Sabeeha S, Crespo José L Activation of Autophagy by Metals in Chlamydomonas reinhardtii. Eukaryotic cell. 2015; 14(9): 964-73.
Gallaher Sean D, Fitz-Gibbon Sorel T, Glaesener Anne G, Pellegrini Matteo, Merchant Sabeeha S Chlamydomonas Genome Resource for Laboratory Strains Reveals a Mosaic of Sequence Variation, Identifies True Strain Histories, and Enables Strain-Specific Studies. The Plant cell. 2015; 27(9): 2335-52.
Ort Donald R, Merchant Sabeeha S, Alric Jean, Barkan Alice, Blankenship Robert E, Bock Ralph, Croce Roberta, Hanson Maureen R, Hibberd Julian M, Long Stephen P, Moore Thomas A, Moroney James, Niyogi Krishna K, Parry Martin A J, Peralta-Yahya Pamela P, Prince Roger C, Redding Kevin E, Spalding Martin H, van Wijk Klaas J, Vermaas Wim F J, von Caemmerer Susanne, Weber Andreas P M, Yeates Todd O, Yuan Joshua S, Zhu Xin Guang Redesigning photosynthesis to sustainably meet global food and bioenergy demand. Proceedings of the National Academy of Sciences of the United States of America. 2015; 112(28): 8529-36.
Fatihi Abdelhak, Latimer Scott, Schmollinger Stefan, Block Anna, Dussault Patrick H, Vermaas Wim F J, Merchant Sabeeha S, Basset Gilles J A Dedicated Type II NADPH Dehydrogenase Performs the Penultimate Step in the Biosynthesis of Vitamin K1 in Synechocystis and Arabidopsis. The Plant cell. 2015; 27(6): 1730-41.
Kropat Janette, Gallaher Sean D, Urzica Eugen I, Nakamoto Stacie S, Strenkert Daniela, Tottey Stephen, Mason Andrew Z, Merchant Sabeeha S Copper economy in Chlamydomonas: prioritized allocation and reallocation of copper to respiration vs. photosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 2015; 112(9): 2644-51.
Allan Christopher M, Awad Agape M, Johnson Jarrett S, Shirasaki Dyna I, Wang Charles, Blaby-Haas Crysten E, Merchant Sabeeha S, Loo Joseph A, Clarke Catherine F Identification of Coq11, a new coenzyme Q biosynthetic protein in the CoQ-synthome in Saccharomyces cerevisiae. The Journal of biological chemistry. 2015; 290(12): 7517-34.
Hong-Hermesdorf Anne, Miethke Marcus, Gallaher Sean D, Kropat Janette, Dodani Sheel C, Chan Jefferson, Barupala Dulmini, Domaille Dylan W, Shirasaki Dyna I, Loo Joseph A, Weber Peter K, Pett-Ridge Jennifer, Stemmler Timothy L, Chang Christopher J, Merchant Sabeeha S Subcellular metal imaging identifies dynamic sites of Cu accumulation in Chlamydomonas. Nature chemical biology. 2015; 11(3): 235.
Fristedt Rikard, Herdean Andrei, Blaby-Haas Crysten E, Mamedov Fikret, Merchant Sabeeha S, Last Robert L, Lundin Björn PHOTOSYSTEM II PROTEIN33, a protein conserved in the plastid lineage, is associated with the chloroplast thylakoid membrane and provides stability to photosystem II supercomplexes in Arabidopsis. Plant physiology. 2015; 167(2): 481-92.
Merchant Sabeeha The plant cell in the new age of scientific publishing. The Plant cell. 2015; 27(2): 303-5.
Fristedt Rikard, Martins Nádia Figueira, Strenkert Daniela, Clarke Cornelia A, Suchoszek Monika, Thiele Wolfram, Schöttler Mark Aurel, Merchant Sabeeha S The thylakoid membrane protein CGL160 supports CF1CF0 ATP synthase accumulation in Arabidopsis thaliana. PloS one. 2015; 10(4): e0121658.
Blaby-Haas Crysten E, Padilla-Benavides Teresita, Stübe Roland, Argüello José M, Merchant Sabeeha S Evolution of a plant-specific copper chaperone family for chloroplast copper homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 2014; 111(50): E5480-7.
Hong-Hermesdorf Anne, Miethke Marcus, Gallaher Sean D, Kropat Janette, Dodani Sheel C, Chan Jefferson, Barupala Dulmini, Domaille Dylan W, Shirasaki Dyna I, Loo Joseph A, Weber Peter K, Pett-Ridge Jennifer, Stemmler Timothy L, Chang Christopher J, Merchant Sabeeha S Subcellular metal imaging identifies dynamic sites of Cu accumulation in Chlamydomonas. Nature chemical biology. 2014; 10(12): 1034-42.
Fristedt Rikard, Williams-Carrier Rosalind, Merchant Sabeeha S, Barkan Alice A thylakoid membrane protein harboring a DnaJ-type zinc finger domain is required for photosystem I accumulation in plants. The Journal of biological chemistry. 2014; 289(44): 30657-67.
Blaby-Haas Crysten E, Merchant Sabeeha S Lysosome-related organelles as mediators of metal homeostasis. The Journal of biological chemistry. 2014; 289(41): 28129-36.
Wakao Setsuko, Chin Brian L, Ledford Heidi K, Dent Rachel M, Casero David, Pellegrini Matteo, Merchant Sabeeha S, Niyogi Krishna K Phosphoprotein SAK1 is a regulator of acclimation to singlet oxygen in Chlamydomonas reinhardtii. eLife. 2014; 3(10): e02286.
Blaby Ian K, Blaby-Haas Crysten E, Tourasse Nicolas, Hom Erik F Y, Lopez David, Aksoy Munevver, Grossman Arthur, Umen James, Dutcher Susan, Porter Mary, King Stephen, Witman George B, Stanke Mario, Harris Elizabeth H, Goodstein David, Grimwood Jane, Schmutz Jeremy, Vallon Olivier, Merchant Sabeeha S, Prochnik Simon The Chlamydomonas genome project: a decade on. Trends in plant science. 2014; 19(10): 672-80.
Goodenough Ursula, Blaby Ian, Casero David, Gallaher Sean D, Goodson Carrie, Johnson Shannon, Lee Jae-Hyeok, Merchant Sabeeha S, Pellegrini Matteo, Roth Robyn, Rusch Jannette, Singh Manmilan, Umen James G, Weiss Taylor L, Wulan Tuya The path to triacylglyceride obesity in the sta6 strain of Chlamydomonas reinhardtii. Eukaryotic cell. 2014; 13(5): 591-613.
Schmollinger Stefan, Mühlhaus Timo, Boyle Nanette R, Blaby Ian K, Casero David, Mettler Tabea, Moseley Jeffrey L, Kropat Janette, Sommer Frederik, Strenkert Daniela, Hemme Dorothea, Pellegrini Matteo, Grossman Arthur R, Stitt Mark, Schroda Michael, Merchant Sabeeha S Nitrogen-Sparing Mechanisms in Chlamydomonas Affect the Transcriptome, the Proteome, and Photosynthetic Metabolism. The Plant cell. 2014; 26(4): 1410-1435.
Fristedt Rikard, Scharff Lars B, Clarke Cornelia A, Wang Qin, Lin Chentao, Merchant Sabeeha S, Bock Ralph RBF1, a plant homolog of the bacterial ribosome-binding factor RbfA, acts in processing of the chloroplast 16S ribosomal RNA. Plant physiology. 2014; 164(1): 201-15.
Blaby-Haas Crysten E, Merchant Sabeeha S Iron sparing and recycling in a compartmentalized cell. Current opinion in microbiology. 2013; 16(6): 677-85.
Blaby Ian K, Glaesener Anne G, Mettler Tabea, Fitz-Gibbon Sorel T, Gallaher Sean D, Liu Bensheng, Boyle Nanette R, Kropat Janette, Stitt Mark, Johnson Shannon, Benning Christoph, Pellegrini Matteo, Casero David, Merchant Sabeeha S Systems-level analysis of nitrogen starvation-induced modifications of carbon metabolism in a Chlamydomonas reinhardtii starchless mutant. The Plant cell. 2013; 25(11): 4305-23.
Urzica Eugen I, Vieler Astrid, Hong-Hermesdorf Anne, Page M Dudley, Casero David, Gallaher Sean D, Kropat Janette, Pellegrini Matteo, Benning Christoph, Merchant Sabeeha S Remodeling of membrane lipids in iron-starved Chlamydomonas. The Journal of biological chemistry. 2013; 288(42): 30246-58.
Hemschemeier Anja, Casero David, Liu Bensheng, Benning Christoph, Pellegrini Matteo, Happe Thomas, Merchant Sabeeha S Copper response regulator1-dependent and -independent responses of the Chlamydomonas reinhardtii transcriptome to dark anoxia. The Plant cell. 2013; 25(9): 3186-211.
Block Anna, Fristedt Rikard, Rogers Sara, Kumar Jyothi, Barnes Brian, Barnes Joshua, Elowsky Christian G, Wamboldt Yashitola, Mackenzie Sally A, Redding Kevin, Merchant Sabeeha S, Basset Gilles J Functional modeling identifies paralogous solanesyl-diphosphate synthases that assemble the side chain of plastoquinone-9 in plastids. The Journal of biological chemistry. 2013; 288(38): 27594-606.
Ming Ray, VanBuren Robert, Liu Yanling, Yang Mei, Han Yuepeng, Li Lei-Ting, Zhang Qiong, Kim Min-Jeong, Schatz Michael C, Campbell Michael, Li Jingping, Bowers John E, Tang Haibao, Lyons Eric, Ferguson Ann A, Narzisi Giuseppe, Nelson David R, Blaby-Haas Crysten E, Gschwend Andrea R, Jiao Yuannian, Der Joshua P, Zeng Fanchang, Han Jennifer, Min Xiang Jia, Hudson Karen A, Singh Ratnesh, Grennan Aleel K, Karpowicz Steven J, Watling Jennifer R, Ito Kikukatsu, Robinson Sharon A, Hudson Matthew E, Yu Qingyi, Mockler Todd C, Carroll Andrew, Zheng Yun, Sunkar Ramanjulu, Jia Ruizong, Chen Nancy, Arro Jie, Wai Ching Man, Wafula Eric, Spence Ashley, Han Yanni, Xu Liming, Zhang Jisen, Peery Rhiannon, Haus Miranda J, Xiong Wenwei, Walsh James A, Wu Jun, Wang Ming-Li, Zhu Yun J, Paull Robert E, Britt Anne B, Du Chunguang, Downie Stephen R, Schuler Mary A, Michael Todd P, Long Steve P, Ort Donald R, Schopf J William, Gang David R, Jiang Ning, Yandell Mark, dePamphilis Claude W, Merchant Sabeeha S, Paterson Andrew H, Buchanan Bob B, Li Shaohua, Shen-Miller Jane Genome of the long-living sacred lotus (Nelumbo nucifera Gaertn.). Genome biology. 2013; 14(5): R41.
Hemschemeier Anja, Düner Melis, Casero David, Merchant Sabeeha S, Winkler Martin, Happe Thomas Hypoxic survival requires a 2-on-2 hemoglobin in a process involving nitric oxide. Proceedings of the National Academy of Sciences of the United States of America. 2013; 110(26): 10854-9.
Malasarn Davin, Kropat Janette, Hsieh Scott I, Finazzi Giovanni, Casero David, Loo Joseph A, Pellegrini Matteo, Wollman Francis-André, Merchant Sabeeha S Zinc deficiency impacts CO2 assimilation and disrupts copper homeostasis in Chlamydomonas reinhardtii. The Journal of biological chemistry. 2013; 288(15): 10672-83.
Glaesener Anne G, Merchant Sabeeha S, Blaby-Haas Crysten E Iron economy in Chlamydomonas reinhardtii. Frontiers in plant science. 2013; 4(9): 337.
Duanmu Deqiang, Casero David, Dent Rachel M, Gallaher Sean, Yang Wenqiang, Rockwell Nathan C, Martin Shelley S, Pellegrini Matteo, Niyogi Krishna K, Merchant Sabeeha S, Grossman Arthur R, Lagarias J Clark Retrograde bilin signaling enables Chlamydomonas greening and phototrophic survival. Proceedings of the National Academy of Sciences of the United States of America. 2013; 110(9): 3621-6.
Hsieh Scott I, Castruita Madeli, Malasarn Davin, Urzica Eugen, Erde Jonathan, Page M Dudley, Yamasaki Hiroaki, Casero David, Pellegrini Matteo, Merchant Sabeeha S, Loo Joseph A The proteome of copper, iron, zinc, and manganese micronutrient deficiency in Chlamydomonas reinhardtii. Molecular & cellular proteomics : MCP. 2013; 12(1): 65-86.
Wang Qin, Fristedt Rikard, Yu Xuhong, Chen Zugen, Liu Hongtao, Lee Yurhee, Guo Hongwei, Merchant Sabeeha S, Lin Chentao The γ-carbonic anhydrase subcomplex of mitochondrial complex I is essential for development and important for photomorphogenesis of Arabidopsis. Plant physiology. 2012; 160(3): 1373-83.
Urzica Eugen I, Casero David, Yamasaki Hiroaki, Hsieh Scott I, Adler Lital N, Karpowicz Steven J, Blaby-Haas Crysten E, Clarke Steven G, Loo Joseph A, Pellegrini Matteo, Merchant Sabeeha S Systems and trans-system level analysis identifies conserved iron deficiency responses in the plant lineage. The Plant cell. 2012; 24(10): 3921-48.
Lee Yueh-Jung, Huang Xinhe, Kropat Janette, Henras Anthony, Merchant Sabeeha S, Dickson Robert C, Chanfreau Guillaume F Sphingolipid signaling mediates iron toxicity. Cell metabolism. 2012; 16(1): 90-6.
Page M Dudley, Allen Michael D, Kropat Janette, Urzica Eugen I, Karpowicz Steven J, Hsieh Scott I, Loo Joseph A, Merchant Sabeeha S Fe Sparing and Fe Recycling Contribute to Increased Superoxide Dismutase Capacity in Iron-Starved Chlamydomonas reinhardtii. The Plant cell. 2012; 16(1): .
Merchant Sabeeha S, Kropat Janette, Liu Bensheng, Shaw Johnathan, Warakanont Jaruswan TAG, You're it! Chlamydomonas as a reference organism for understanding algal triacylglycerol accumulation. Current opinion in biotechnology. 2012; 23(3): 352-63.
Fischer Beat B, Ledford Heidi K, Wakao Setsuko, Huang ShihYau Grace, Casero David, Pellegrini Matteo, Merchant Sabeeha S, Koller Andreas, Eggen Rik I L, Niyogi Krishna K SINGLET OXYGEN RESISTANT 1 links reactive electrophile signaling to singlet oxygen acclimation in Chlamydomonas reinhardtii. Proceedings of the National Academy of Sciences of the United States of America. 2012; 109(20): E1302-11.
Blaby-Haas Crysten E, Merchant Sabeeha S The ins and outs of algal metal transport. Biochimica et biophysica acta. 2012; 287(19): .
Boyle Nanette R, Page Mark Dudley, Liu Bensheng, Blaby Ian K, Casero David, Kropat Janette, Cokus Shawn J, Hong-Hermesdorf Anne, Shaw Johnathan, Karpowicz Steven J, Gallaher Sean D, Johnson Shannon, Benning Christoph, Pellegrini Matteo, Grossman Arthur, Merchant Sabeeha S Three acyltransferases and nitrogen-responsive regulator are implicated in nitrogen starvation-induced triacylglycerol accumulation in Chlamydomonas. The Journal of biological chemistry. 2012; 287(19): 15811-25.
Fang Wei, Si Yaqing, Douglass Stephen, Casero David, Merchant Sabeeha S, Pellegrini Matteo, Ladunga Istvan, Liu Peng, Spalding Martin H Transcriptome-Wide Changes in Chlamydomonas reinhardtii Gene Expression Regulated by Carbon Dioxide and the CO2-Concentrating Mechanism Regulator CIA5/CCM1. The Plant cell. 2012; 24(5): 1876-93.
Urzica Eugen I, Adler Lital N, Page M Dudley, Linster Carole L, Arbing Mark A, Casero David, Pellegrini Matteo, Merchant Sabeeha S, Clarke Steven G Impact of oxidative stress on ascorbate biosynthesis in Chlamydomonas via regulation of the VTC2 gene encoding a GDP-L-galactose phosphorylase. The Journal of biological chemistry. 2012; 287(17): 14234-45.
Merchant Sabeeha S, Helmann John D Elemental economy: microbial strategies for optimizing growth in the face of nutrient limitation. Advances in microbial physiology. 2012; 60(2): 91-210.
Bernal María, Casero David, Singh Vasantika, Wilson Grandon T, Grande Arne, Yang Huijun, Dodani Sheel C, Pellegrini Matteo, Huijser Peter, Connolly Erin L, Merchant Sabeeha S, Krämer Ute Transcriptome sequencing identifies SPL7-regulated copper acquisition genes FRO4/FRO5 and the copper dependence of iron homeostasis in Arabidopsis. The Plant cell. 2012; 24(2): 738-61.
Lopez David, Casero David, Cokus Shawn J, Merchant Sabeeha S, Pellegrini Matteo Algal Functional Annotation Tool: a web-based analysis suite to functionally interpret large gene lists using integrated annotation and expression data. BMC bioinformatics. 2011; 12(10): 282.
Kropat Janette, Hong-Hermesdorf Anne, Casero David, Ent Petr, Castruita Madeli, Pellegrini Matteo, Merchant Sabeeha S, Malasarn Davin A revised mineral nutrient supplement increases biomass and growth rate in Chlamydomonas reinhardtii. The Plant journal : for cell and molecular biology. 2011; 66(5): 770-80.
Karpowicz Steven J, Prochnik Simon E, Grossman Arthur R, Merchant Sabeeha S The GreenCut2 Resource, a Phylogenomically Derived Inventory of Proteins Specific to the Plant Lineage. The Journal of biological chemistry. 2011; 286(24): 21427-39.
Castruita Madeli, Casero David, Karpowicz Steven J, Kropat Janette, Vieler Astrid, Hsieh Scott I, Yan Weihong, Cokus Shawn, Loo Joseph A, Benning Christoph, Pellegrini Matteo, Merchant Sabeeha S Systems Biology Approach in Chlamydomonas Reveals Connections between Copper Nutrition and Multiple Metabolic Steps. The Plant cell. 2011; 23(4): 1273-92.
Gabilly Stéphane T, Kropat Janette, Karamoko Mohamed, Page M Dudley, Nakamoto Stacie S, Merchant Sabeeha S, Hamel Patrice P A novel component of the disulfide-reducing pathway required for cytochrome c assembly in plastids. Genetics. 2011; 187(3): 793-802.
Sommer Frederik, Kropat Janette, Malasarn Davin, Grossoehme Nicholas E, Chen Xiaohua, Giedroc David P, Merchant Sabeeha S The CRR1 nutritional copper sensor in Chlamydomonas contains two distinct metal-responsive domains. The Plant cell. 2010; 22(12): 4098-113.
Grossman Arthur R, Karpowicz Steven J, Heinnickel Mark, Dewez David, Hamel Blaise, Dent Rachel, Niyogi Krishna K, Johnson Xenie, Alric Jean, Wollman Francis-André, Li Huiying, Merchant Sabeeha S Phylogenomic analysis of the Chlamydomonas genome unmasks proteins potentially involved in photosynthetic function and regulation. Photosynthesis research. 2010; 106(1-2): 3-17.
Knight Mary Jane, Joubert Marisa K, Plotkowski Megan L, Kropat Janette, Gingery Mari, Sakane Fumio, Merchant Sabeeha S, Bowie James U Zinc binding drives sheet formation by the SAM domain of diacylglycerol kinase δ. Biochemistry. 2010; 49(44): 9667-76.
Merchant Sabeeha S The elements of plant micronutrients. Plant physiology. 2010; 154(2): 512-5.
Gabilly Stéphane T, Dreyfuss Beth Welty, Karamoko Mohamed, Corvest Vincent, Kropat Janette, Page M Dudley, Merchant Sabeeha S, Hamel Patrice P CCS5, a thioredoxin-like protein involved in the assembly of plastid c-type cytochromes. The Journal of biological chemistry. 2010; 285(39): 29738-49.
Chodavarapu Ramakrishna K, Feng Suhua, Bernatavichute Yana V, Chen Pao-Yang, Stroud Hume, Yu Yanchun, Hetzel Jonathan A, Kuo Frank, Kim Jin, Cokus Shawn J, Casero David, Bernal Maria, Huijser Peter, Clark Amander T, Krämer Ute, Merchant Sabeeha S, Zhang Xiaoyu, Jacobsen Steven E, Pellegrini Matteo Relationship between nucleosome positioning and DNA methylation. Nature. 2010; 466(7304): 388-92.
Terauchi Aimee M, Peers Graham, Kobayashi Marilyn C, Niyogi Krishna K, Merchant Sabeeha S Trophic status of Chlamydomonas reinhardtii influences the impact of iron deficiency on photosynthesis. Photosynthesis research. 2010; 105(1): 39-49.
Merchant, S.S. Green with envy: on citation of the chlorophyll assay. Commentary on Arnon DI (1949) Copper enzymes in isolated chloroplasts. Plant physiology. 2010; 24: 1-15.
González-Ballester David, Casero David, Cokus Shawn, Pellegrini Matteo, Merchant Sabeeha S, Grossman Arthur R RNA-seq analysis of sulfur-deprived Chlamydomonas cells reveals aspects of acclimation critical for cell survival. The Plant cell. 2010; 22(6): 2058-84.
Hirasawa Masakazu, Tripathy Jatindra N, Sommer Frederik, Somasundaram Ramasamy, Chung Jung-Sung, Nestander Matthew, Kruthiventi Mahima, Zabet-Moghaddam Masoud, Johnson Michael K, Merchant Sabeeha S, Allen James P, Knaff David B Enzymatic properties of the ferredoxin-dependent nitrite reductase from Chlamydomonas reinhardtii. Evidence for hydroxylamine as a late intermediate in ammonia production. Photosynthesis research. 2010; 103(2): 67-77.
Haas Crysten E, Rodionov Dmitry A, Kropat Janette, Malasarn Davin, Merchant Sabeeha S, de Crécy-Lagard Valérie A subset of the diverse COG0523 family of putative metal chaperones is linked to zinc homeostasis in all kingdoms of life. BMC genomics. 2009; 10(47): 470.
Petroutsos Dimitris, Terauchi Aimee M, Busch Andreas, Hirschmann Ingrid, Merchant Sabeeha S, Finazzi Giovanni, Hippler Michael PGRL1 participates in iron-induced remodeling of the photosynthetic apparatus and in energy metabolism in Chlamydomonas reinhardtii. The Journal of biological chemistry. 2009; 284(47): 32770-81.
Terauchi Aimee M, Lu Shu-Fen, Zaffagnini Mirko, Tappa Shane, Hirasawa Masakazu, Tripathy Jatindra N, Knaff David B, Farmer Patrick J, Lemaire Stéphane D, Hase Toshiharu, Merchant Sabeeha S Pattern of expression and substrate specificity of chloroplast ferredoxins from Chlamydomonas reinhardtii. The Journal of biological chemistry. 2009; 284(38): 25867-78.
Merchant Sabeeha S His protects heme as it crosses the membrane. Proceedings of the National Academy of Sciences of the United States of America. 2009; 106(25): 10069-70.
Long Joanne C, Merchant Sabeeha S Photo-oxidative stress impacts the expression of genes encoding iron metabolism components in Chlamydomonas. Photochemistry and photobiology. 2009; 84(6): 1395-403.
Allen Michael D, Kropat Janette, Merchant Sabeeha S Regulation and localization of isoforms of the aerobic oxidative cyclase in Chlamydomonas reinhardtii. Photochemistry and photobiology. 2009; 84(6): 1336-42.
Page M Dudley, Kropat Janette, Hamel Patrice P, Merchant Sabeeha S Two Chlamydomonas CTR copper transporters with a novel cys-met motif are localized to the plasma membrane and function in copper assimilation. The Plant cell. 2009; 21(3): 928-43.
Chen, J.-C., Hsieh, S.I., Kropat, J., Merchant, S. A Ferroxidase Encoded by FOX1 Contributes to Iron Assimilation under Conditions of Poor Iron Nutrition in Chlamydomonas. Eukaryot. Cell. 2008; 7(3): 541-545.
Hanikenne, M., Merchant, S.S., Hamel, P.P. Transition metal nutrition: a balance between deficiency and toxicity . The Chlamydomonas Sourcebook (2nd Edition) 2008; 2: 333-400.
Long Joanne C, Sommer Frederik, Allen Michael D, Lu Shu-Fen, Merchant Sabeeha S FER1 and FER2 encoding two ferritin complexes in Chlamydomonas reinhardtii chloroplasts are regulated by iron. Genetics. 2008; 179(1): 137-47.
Chen Jen-Chih, Hsieh Scott I, Kropat Janette, Merchant Sabeeha S A ferroxidase encoded by FOX1 contributes to iron assimilation under conditions of poor iron nutrition in Chlamydomonas. Eukaryotic cell. 2008; 7(3): 541-5.
Allen Michael D, del Campo José A, Kropat Janette, Merchant Sabeeha S FEA1, FEA2, and FRE1, encoding two homologous secreted proteins and a candidate ferrireductase, are expressed coordinately with FOX1 and FTR1 in iron-deficient Chlamydomonas reinhardtii. Eukaryotic cell. 2007; 6(10): 1841-52.
Merchant Sabeeha S, Prochnik Simon E, Vallon Olivier, Harris Elizabeth H, Karpowicz Steven J, Witman George B, Terry Astrid, Salamov Asaf, Fritz-Laylin Lillian K, Maréchal-Drouard Laurence, Marshall Wallace F, Qu Liang-Hu, Nelson David R, Sanderfoot Anton A, Spalding Martin H, Kapitonov Vladimir V, Ren Qinghu, Ferris Patrick, Lindquist Erika, Shapiro Harris, Lucas Susan M, Grimwood Jane, Schmutz Jeremy, Cardol Pierre, Cerutti Heriberto, Chanfreau Guillaume, Chen Chun-Long, Cognat Valérie, Croft Martin T, Dent Rachel, Dutcher Susan, Fernández Emilio, Fukuzawa Hideya, González-Ballester David, González-Halphen Diego, Hallmann Armin, Hanikenne Marc, Hippler Michael, Inwood William, Jabbari Kamel, Kalanon Ming, Kuras Richard, Lefebvre Paul A, Lemaire Stéphane D, Lobanov Alexey V, Lohr Martin, Manuell Andrea, Meier Iris, Mets Laurens, Mittag Maria, Mittelmeier Telsa, Moroney James V, Moseley Jeffrey, Napoli Carolyn, Nedelcu Aurora M, Niyogi Krishna, Novoselov Sergey V, Paulsen Ian T, Pazour Greg, Purton Saul, Ral Jean-Philippe, Riaño-Pachón Diego Mauricio, Riekhof Wayne, Rymarquis Linda, Schroda Michael, Stern David, Umen James, Willows Robert, Wilson Nedra, Zimmer Sara Lana, Allmer Jens, Balk Janneke, Bisova Katerina, Chen Chong-Jian, Elias Marek, Gendler Karla, Hauser Charles, Lamb Mary Rose, Ledford Heidi, Long Joanne C, Minagawa Jun, Page M Dudley, Pan Junmin, Pootakham Wirulda, Roje Sanja, Rose Annkatrin, Stahlberg Eric, Terauchi Aimee M, Yang Pinfen, Ball Steven, Bowler Chris, Dieckmann Carol L, Gladyshev Vadim N, Green Pamela, Jorgensen Richard, Mayfield Stephen, Mueller-Roeber Bernd, Rajamani Sathish, Sayre Richard T, Brokstein Peter, Dubchak Inna, Goodstein David, Hornick Leila, Huang Y Wayne, Jhaveri Jinal, Luo Yigong, Martínez Diego, Ngau Wing Chi Abby, Otillar Bobby, Poliakov Alexander, Porter Aaron, Szajkowski Lukasz, Werner Gregory, Zhou Kemin, Grigoriev Igor V, Rokhsar Daniel S, Grossman Arthur R The Chlamydomonas genome reveals the evolution of key animal and plant functions. Science (New York, N.Y.). 2007; 318(5848): 245-50.
Allen, M.D., del Campo, J.A., Kropat, J. Merchant, S.S. FEA1, FEA2 and FRE1, Encoding Two Homologous Secreted Proteins and a Candidate Ferrireductase, are Expressed Coordinately with FOX1 and FTR1 in Iron-Deficient Chlamydomonas reinhardtii. Eukaryot. Cell. 2007; 6: 1841-1852.
Allen, M.D., Kropat, J. ,Tottey, S., Del Campo, J.A., Merchant, S. Manganese Deficiency in Chlamydomonas Results in Loss of Photosystem II and MnSOD Function, Sensitivity to Peroxides, and Secondary Phosphorus and Iron Deficiency. Plant Physiology. 2007; 143: 263-277.
Grossman, A.R., Croft, M., Gladyshev, V.N., Merchant, S., Posewitz, M.C., Prochnik, S., Spalding, M.H. Novel metabolism in Chlamydomonas through the lens of genomics. Current Opinion in Plant Biology. 2007; 10(2): 190-198.
Merchant, S.S., Prochnik, S.E., Vallon, O., Harris, E.H., Karpowicz, S.J., Witman, G.B., Terry, A., Salamov, A., Fritz-Laylin, L.K., Marechal-Drouard, L., Marshall, W.F., Qu, L.-H., Nelson, D.R., Sanderfoot, A.A., Spalding, M.H., Kapitonov, V.V., Ren, Q., Ferris, P., Lindquist, E., Shapiro, H., Grimwood, J., Schmutz, J., Lucas, S., Chlamydomonas community annotation team, JGI annotation team, Grigoriev, I.V., Rokhsar, D.S., Grossman, A.R. The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant Functions. Science. 2007; 318: 245-250.
Palenik, B., Grimwood, J., Aerts, A., Rouze, P., Salamov, A., Putnam, N., Dupont C., Jorgensen, R., Derelle, E., Rombauts, S., Zhou, K., Otillar, R., Merchant, S., Podell, S., Gaasterland, T., Napoli, C., Gendler, K., Manuell, A., Tai, V., Vallon, O., Piganeau, G., Jancek, S., Heijde, M., Jabbari, K., Bowler, C., Lohr, M., Robbens, S., Werner, G., Dubchak, I., Pazour, G.J., Ren, Q., Paulsen, I., Delwiche, C., Schmutz, J., Rokhsar, D., van de Peer, Y., Moreau, H., Grigoriev, I. Tiny eukaryotes provide genomic insights into the paradox of the plankton. Proc. Natl. Acad. Sci. USA. 2007; 104: 7705-7710.
Palenik Brian, Grimwood Jane, Aerts Andrea, Rouzé Pierre, Salamov Asaf, Putnam Nicholas, Dupont Chris, Jorgensen Richard, Derelle Evelyne, Rombauts Stephane, Zhou Kemin, Otillar Robert, Merchant Sabeeha S, Podell Sheila, Gaasterland Terry, Napoli Carolyn, Gendler Karla, Manuell Andrea, Tai Vera, Vallon Olivier, Piganeau Gwenael, Jancek Séverine, Heijde Marc, Jabbari Kamel, Bowler Chris, Lohr Martin, Robbens Steven, Werner Gregory, Dubchak Inna, Pazour Gregory J, Ren Qinghu, Paulsen Ian, Delwiche Chuck, Schmutz Jeremy, Rokhsar Daniel, Van de Peer Yves, Moreau Hervé, Grigoriev Igor V The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(18): 7705-10.
Allen Michael D, Kropat Janette, Tottey Stephen, Del Campo José A, Merchant Sabeeha S Manganese deficiency in Chlamydomonas results in loss of photosystem II and MnSOD function, sensitivity to peroxides, and secondary phosphorus and iron deficiency. Plant physiology. 2007; 143(1): 263-77.
Merchant Sabeeha S, Sagasti Alvaro Precious metal economy. Cell metabolism. 2006; 4(2): 99-101.
Merchant Sabeeha S, Allen Michael D, Kropat Janette, Moseley Jeffrey L, Long Joanne C, Tottey Stephen, Terauchi Aimee M Between a rock and a hard place: trace element nutrition in Chlamydomonas. Biochimica et biophysica acta. 2006; 1763(7): 578-94.
Merchant, S., Allen, M.D., Kropat, J., Moseley, J.L., Long, J.C., Tottey, S., Terauchi, A.M. Between a rock and a hard place: trace element nutrition in Chlamydomonas. Biochim. Biophys. Acta. 2006; 1763: 578-594.
Kropat Janette, Tottey Stephen, Birkenbihl Rainer P, Depège Nathalie, Huijser Peter, Merchant Sabeeha A regulator of nutritional copper signaling in Chlamydomonas is an SBP domain protein that recognizes the GTAC core of copper response element. Proceedings of the National Academy of Sciences of the United States of America. 2005; 102(51): 18730-5.
Bernard Delphine G, Quevillon-Cheruel Sophie, Merchant Sabeeha, Guiard Bernard, Hamel Patrice P Cyc2p, a membrane-bound flavoprotein involved in the maturation of mitochondrial c-type cytochromes. The Journal of biological chemistry. 2005; 280(48): 39852-9.
Kropat J, Tottey S, Birkenbihl RP, Depege N, Huijser P, Merchant S. A regulator of nutritional copper signaling in Chlamydomonas is an SBP domain protein that recognizes the GTAC core of copper response element. Proc. Nat.l Acad. Sci U S A. 2005; 102(51): 18730-5.
Rzeznicka Kamila, Walker Caroline J, Westergren Tomas, Kannangara C Gamini, von Wettstein Diter, Merchant Sabeeha, Gough Simon P, Hansson Mats Xantha-l encodes a membrane subunit of the aerobic Mg-protoporphyrin IX monomethyl ester cyclase involved in chlorophyll biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 2005; 102(16): 5886-91.
Merchant Sabeeha, Sawaya Michael R The light reactions: a guide to recent acquisitions for the picture gallery. The Plant cell. 2005; 17(3): 648-63.
Eriksson Mats, Moseley Jeffrey L, Tottey Stephen, Del Campo Jose A, Quinn Jeanette, Kim Youngbae, Merchant Sabeeha Genetic dissection of nutritional copper signaling in chlamydomonas distinguishes regulatory and target genes. Genetics. 2004; 168(2): 795-807.
Page M L Dudley, Hamel Patrice P, Gabilly Stéphane T, Zegzouti Hicham, Perea John V, Alonso José M, Ecker Joseph R, Theg Steven M, Christensen Sioux K, Merchant Sabeeha A homolog of prokaryotic thiol disulfide transporter CcdA is required for the assembly of the cytochrome b6f complex in Arabidopsis chloroplasts. The Journal of biological chemistry. 2004; 279(31): 32474-82.
Del Campo José A, Quinn Jeanette M, Merchant Sabeeha Evaluation of oxygen response involving differential gene expression in Chlamydomonas reinhardtii. Methods in enzymology. 2004; 381(31): 604-17.
Page MD, Hamel PO, Gabilly ST, Zegzouti H, Perea JV, Alonso JM, Ecker JR, Theg S, Christiansen S, Merchant S A homolog of prokaryotic thio-disulfide transporter CcdA is required for the assembly of the cytochrome c6f complex in Arabidopsis chloroplasts. Journal of Biological Chemistry 2004; 279: 32474-82.
Eriksson M, Mosely JL, Tottey S, del Campo JA, Quinn J, Kim Y, Merchant S Molecular genetic dissection of nutritional copper signalling in Chlamydomonas distinguishes regulatory and target genes. Genetics 2004; 168: 795-807.
Tottey S, Block MA, Allen M, Westergren T, Albrieux C, Scheller HV, Merchant S, Jensen PE Arabidopsis CHL27, located in both envelope and thylakoid membranes, is required for the synthesis of protochlorophyllide. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(26): 16119-24.
Tottey Stephen, Block Maryse A, Allen Michael, Westergren Tomas, Albrieux Catherine, Scheller Henrik V, Merchant Sabeeha, Jensen Poul Erik Arabidopsis CHL27, located in both envelope and thylakoid membranes, is required for the synthesis of protochlorophyllide. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(26): 16119-24.
Bernard Delphine G, Gabilly Stéphane T, Dujardin Geneviève, Merchant Sabeeha, Hamel Patrice P Overlapping specificities of the mitochondrial cytochrome c and c1 heme lyases. The Journal of biological chemistry. 2003; 278(50): 49732-42.
Quinn Jeanette M, Kropat Janette, Merchant Sabeeha Copper response element and Crr1-dependent Ni(2+)-responsive promoter for induced, reversible gene expression in Chlamydomonas reinhardtii. Eukaryotic cell. 2003; 2(5): 995-1002.
Hamel Patrice P, Dreyfuss Beth Welty, Xie Zhiyi, Gabilly Stéphane T, Merchant Sabeeha Essential histidine and tryptophan residues in CcsA, a system II polytopic cytochrome c biogenesis protein. The Journal of biological chemistry. 2003; 278(4): 2593-603.
Dreyfuss Beth Welty, Hamel Patrice P, Nakamoto Stacie S, Merchant Sabeeha Functional analysis of a divergent system II protein, Ccs1, involved in c-type cytochrome biogenesis. The Journal of biological chemistry. 2003; 278(4): 2604-13.
Moseley Jeffrey L, Allinger Tanja, Herzog Sebastian, Hoerth Patric, Wehinger Elke, Merchant Sabeeha, Hippler Michael Adaptation to Fe-deficiency requires remodeling of the photosynthetic apparatus. The EMBO journal. 2002; 21(24): 6709-20.
La Fontaine Sharon, Quinn Jeanette M, Nakamoto Stacie S, Page M Dudley, Göhre Vera, Moseley Jeffrey L, Kropat Janette, Merchant Sabeeha Copper-dependent iron assimilation pathway in the model photosynthetic eukaryote Chlamydomonas reinhardtii. Eukaryotic cell. 2002; 1(5): 736-57.
Moseley JL, Page MD, Alder NP, Eriksson M, Quinn J, Soto F, Theg M, Hippler M, Merchant S Reciprocal expression of two candidate di-iron enymes affecting photosystem I and light-harvesting complex accumulation. Plant Cell 2002; 14: 673-688.
Moseley Jeffrey L, Page M Dudley, Alder Nancy P, Eriksson Mats, Quinn Jeanette, Soto Feiris, Theg Steven M, Hippler Michael, Merchant Sabeeha Reciprocal expression of two candidate di-iron enzymes affecting photosystem I and light-harvesting complex accumulation. The Plant cell. 2002; 14(3): 673-88.
Quinn Jeanette M, Eriksson Mats, Moseley Jeffrey L, Merchant Sabeeha Oxygen deficiency responsive gene expression in Chlamydomonas reinhardtii through a copper-sensing signal transduction pathway. Plant physiology. 2002; 128(2): 463-71.
Springer S, Chen E, Duden R, Marzioch M, Rowley A, Hamamoto S, Merchant S, Schekman R The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci 2000; 97: 4034-4039.
Koehler CM, Merchant S, Schatz G How membrane proteins travel across the mitochondrial intermembrane space. Trends in Biochemical Sciences. 1999; 24(11): 428-32.
Koehler CM, Merchant S, Oppliger W, Schmid K, Jarosch E, Dolfini L, Junne T, Schatz G, Tokatlidis K Tim9p, an essential partner subunit of Tim10p for the import of mitochondrial carrier proteins. The EMBO J. 1998; 17(22): 6477-86.
Merchant Sabeeha, Dreyfuss Beth Welty POSTTRANSLATIONAL ASSEMBLY OF PHOTOSYNTHETIC METALLOPROTEINS. Annual review of plant physiology and plant molecular biology. 1998; 49: 25-51.
Li HH, Merchant S Degradation of plastocyanin in copper-deficient Chlamydomonas reinhardtii. Evidence for a protease-susceptible conformation of the apoprotein and regulated proteolysis. The Journal of Biological Chemistry. 1995; 270(40): 23504-10.
Quinn JM, Merchant S Two copper-responsive elements associated with the Chlamydomonas Cyc6 gene function as targets for transcriptional activators. The Plant Cell. 1995; 7(5): 623-8.
Howe G, Merchant S Maturation of thylakoid lumen proteins proceeds post-translationally through an intermediate in vivo. Proceedings of the National Academy of Sciences of the United States of America. 1993; 90(5): 1862-6.