A selected list of publications:
Liu Bin, Tahk Samuel, Yee Kathleen M, Yang Randy, Yang Yonghui, Mackie Ryan, Hsu Cary, Chernishof Vasili, O'Brien Neil, Jin Yusheng, Fan Guoping, Lane Timothy F, Rao Jianyu, Slamon Dennis, Shuai Ke
PIAS1 regulates breast tumorigenesis through selective epigenetic gene
silencing
PloS one,
2014; 9(2):
e89464.
Shalizi A.
Bilimoria P.M.
Stegmuller J.
Gaudilliere B.
Yang Y.
Shuai K.
Bonni A.
PIASx is a MEF2 SUMO E3 ligase that promotes postsynaptic dendritic morphogenesis,
J Neurosci,
2007; 27:
10037-46.
Liu B, Yang Y, Chernishof V, Ogorzalek-Loo R, Jang H, Tahk S, Yang R, Mink S, Schultz D, Bellone C, Loo J, Shuai K
Pro-Inflammatory stimuli induce IKKa-mediated Phosophorylation of PIAS1 to restrict inflammation and immunity,
Cell,
2007; 129:
903-904.
Dadke S, Cotteret S, Yip SC, Jaffer Z, Haj F, Ivanov A, Rauscher F, Shuai K, Ng T, Neel B, Chernoff J
Regulation of Protein Tyrosine Phosphatase (PTP) 1B by sumoylation,
Nat. Cell Biol,
2007; 9:
80-85.
Shuai K
Regulation of cytokine signaling pathways by PIAS proteins,
Cell Res,
2006; 16:
196-202.
Fan G, Martinowich MH, Chin F, He SD, Fouse L, Hutnick D, Hattori W, Ge Y, Shen H, Wu J, ten Hoeve J, Shuai K, Sun YE
DNA Methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling,
Development,
2005; 132:
3345-3356.
Henriksen MA, Zhong M, Takeuchi K, Schafer O, Bouman L, ten Hoeve J, Ren S, Chen X, Shuai K*, Darnell JE* (*co-corresponding authors)
Implications of an anti-parallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle,
Proc. Natl. Acad. Sci,
2005; 102:
3966-3971.
Zhong M, Henriksen MA, Takeuchi K, Schaefer O, Liu B, ten Hoeve J, Ren Z, Mao X, Chen X, Shuai K, Darnell JE
Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle
Proceedings of the National Academy of Sciences of the United States of America. ,
2005; 102(11):
3966-71.
Shuai K, Liu B
Regulation of gene-activation pathways by PIAS proteins in the immune system,
Nat. Rev. Immunol,
2005; 5:
593-605.
Long J, Matsuura I, He D, Wang G, Shuai K, Liu F
Repression of Smad transcriptional activity by PIASy,
Proc. Natl. Acad. of Sci,
2003; 100:
9791-9796.
ten Hoeve J, Ibarra-Sanchez MJ, Yu Y, Zhu W, Tremblay M, David M, Shuai K
Identification of a nuclear Stat1 protein tyrosine phosphatase,
Mol. Cell. Biol,
2002; 22:
5662-5668.
Mowen KA, Tang J, Zhu W, Schurter BT, Shuai K, Herschman HR, David M
Arginine methylation of STAT1 modulates IFNa/b-induced transcription,
Cell,
2001; 104:
731-741.
Liu B, Shuai K
Indiction of apoptosis by protein inhibitor of activated Stat 1 through c-Jun NH2-terminal kinase activation,
J. Biol. Chem,
2001; 276:
36624-36631.
Liao J, Fu Y, Shuai K
Distinct roles of the NH2-terminal and COOH-terminal domains of PIAS1 in cytokine-induced PIAS1-Stat1 interaction,
Proc. Natl. Acad. Sci,
2000; 97:
5267-5272.
Graeber TG, Shuai K
Rapid gene repression triggered by interlukin-6 at the onset of monocyte differentiation,
Biochem. Biophsy. Res. Commun,
2000; 267:
863-869.
Roedel B, Tavassoli K, Karsunky H, Schmidt T, Bachmann M, Schaper F, Heinrich P, Shuai K, Elsaesser HP, Moeroey T
The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3,
EMBO J,
2000; 19:
5845-5855.
Shuai K
The STAT family of proteins in cytokine signaling,
Prog. Biophys. Mol. Biol,
1999; 71:
405-422.
Garcia VE, Jullien D, Song M, Uyemura K, Shuai K, Morita CT, Modlin RL
IL-15 enhances the response of human gamma/delta T cells to nonpeptide microbial antigens,
J. Immunology,
1998; 160:
4322-4329.
Mark M Song, Ke Shuai
The Suppressor of Cytokine Signaling (SOCS) 1 and SOCS3 but Not SOCS2 Proteins Inhibit Interferon-mediated Antiviral and Antiproliferative Activities,
J. Biol. Chem,
1998; 273:
35056-35062.
Sadowski HB, Shuai K, Darnell JE jr, Gilman MZ
A Common Nuclear Signal Transduction Pathway Activated by Growth Factor and Cytokine Receptors,
Science,
1993; 261:
1739-44.
Shuai K, Ziemiecki A, Wilks AF, Harpur AG, Sadowski HB, Gilman MZ, Darnell JE Jr
Polypeptide Signaling to the Nucleus through Tyrosine Phosphorylation of Jak and Stat Proteins,
Nature,
1993; 366:
580-3.