A selected list of publications:
Lu, J.; Chan, L.; Fiji, H. D. G.; Dahl, R.; Kwon, O.; Tamanoi, F
In vivo anticancer effect of a novel inhibitor of protein geranylgeranyltransferase I,
Mol. Cancer Ther,
2009; 8:
1218-1226.
Guo, H.; Xu, Q.; Kwon, O.
Phosphine-Promoted [3+3] Annulation of Aziridines with Allenoates: A Facile Entry into Highly Functionalized Tetrahydropyridines,
J. Am. Chem. Soc,
2009; 131:
6318-6319.
Creech, G. S.; Kwon, O.
Alcohol-Assisted Phosphine Catalysis: One-Step Synthesis of Dihydropyrone from Aldehyde and Allenoate,
Org. Lett,
2008; 10:
429−432.
Watanabe, M.; Fiji, H. D. G.; Guo, L.; Umetsu, A.; Kinderman, S. S.; Slamon, D. J.; Kwon, O.; Tamanoi, F.
Inhibitors of protein geranylgeranyltransferase-I and Rab geranylgeranyltransferase identified from a library of allenoate derived compounds,
J. Biol. Chem,
2008; 283:
9571−9579.
Creech, G. S.; Zhu, X.; Fonovic, B.; Dudding, T.; Kwon, O.
Theory-Guided Design of Brønsted Acid-Assisted Phosphine Catalysis: Synthesis of Dihydropyrones from Aldehydes and Allenoates,
Tetrahedron,
2008; 64:
6935−6942.
Sriramurthy, V.; Barcan, G. A.; Kwon, O.
Bisphosphine-Catalyzed Mixed Double-Michael Reactions: Asymmetric Synthesis of Oxazolidines, Thiazolidines, and Pyrrolidines,
J. Am. Chem. Soc,
2007; 129:
12928−12929 (Highlighted in SYNFACTS 2008, 19; Featured as a Synstory in SYNFORM 2008, A10−A12).
Mercier, E.; Fonovic, B.; Henry, C. E.; Kwon, O.; Dudding, T.
Phosphine Triggered [3+2] Allenoate-Acrylate Annulation: A Mechanistic Enlightenment,
Tetrahedron Lett,
2007; 48:
3617−3620.
Henry, C. E.; Kwon, O.
Phosphine-Catalyzed Synthesis of Highly Functionalized Coumarins,
Org. Lett,
2007; 9:
3069−3072 (Highlighted in SYNFACTS 2007, 1145).
Tran, Y. S.; Kwon, O.
Phosphine-Catalyzed [4 + 2] Annulation: Synthesis of Cyclohexenes,
J. Am. Chem. Soc,
2007; 129:
12632−12633.
Castellano, S.; Fiji, H. D. G.; Kinderman, S. S.; Watanabe, M.; De Leon, P.; Tamanoi, F.; Kwon, O.
Small-Molecule Inhibitors of Protein Geranylgeranyltransferase Type I,
J. Am. Chem. Soc,
2007; 129:
5843−5845.
Zhu, X.; Henry, C. E.; Kwon, O.
Stable Tetravalent Phosphonium Enolate Zwitterions,
J. Am. Chem. Soc,
2007; 129:
6722−6723.
Dudding, T.; Kwon, O.; Mercier, E.
Theoretical Rationale for Regioselection in Phosphine Catalyzed Allenoate Additions to Acrylates, Imines and Aldehydes,
Org. Lett,
2006; 8:
3643−3646.
Zhu, X.-F.; Henry, C. E.; Kwon, O.
A highly diastereoselective synthesis of 3-carbethoxy-2,5-disubstituted-3-pyrrolines by phosphine catalysis,
Tetrahedron,
2005; 61:
6276-6282.
Tran, Y. S.; Kwon, O.
An Application of the Phosphine-Catalyzed [4 + 2] Annulation in Indole Alkaloid Synthesis: Formal Syntheses of (±)-Alstonerine and (±)-Macroline,
Org. Lett,
2005; 7:
4289−4291.
Zhu, X.-F.; Henry, C. E.; Wang, J.; Dudding, T.; Kwon, O.
Phosphine-Catalyzed Synthesis of 1,3- Dioxan-4-ylidenes,
Org. Lett,
2005; 7:
1387-1390.
Zhu, X.-F.; Schaffner, A.-P.; Li, R. C.; Kwon, O.
Phosphine-Catalyzed Synthesis of 6-Substituted 2-pyrones: Manifestation of E/Z-Isomerism in the Zwitterionic Intermediate,
Org. Lett,
2005; 7:
2977-2980.
Du, X.; Chu, H. V.; Kwon, O.
A Concise Synthesis of the Functionalized [5-7-6] Tricyclic Skeleton of Guanacastepene A,
Tetrahedron Lett,
2004; 6:
8843-8846.
Schmidt, D.R.; Kwon, O.; Schreiber, S.L.
Macrolactones in Diversity-Oriented Synthesis: Preparation of a Pilot Library and Exploration of Factors Controlling Macrocyclization,
J. Comb. Chem,
2004; 6:
286-292.
Zhu, X.-F.; Lan, J.; Kwon, O.
An Expedient Phosphine-Catalyzed [4+2] Annulation: Synthesis of Highly Functionalized Tetrahydropyridines,
J. Am. Chem. Soc,
2003; 125:
4716-4717.
Du, X.; Chu, H. V.; Kwon, O.
Synthesis of the [5-7-6] Tricyclic Core of Guanacastepene A via an Intramolecular Mukaiyama Aldol Reaction,
Org. Lett,
2003; 5:
1923-1926.