Yibin Wang, Ph.D.

Mailing Address:
UCLA, David Geffen School of Medicine
Department of Anesthesiology
Division of Molecular Medicine
650 Charles E Young Dr.
CHS/BH569
Los Angeles, CA 90095

Work Address:
CHS BH-569
Campus - 711520
CA

Affiliations
Affiliations
Vice-Chair, Research and Professor, Anesthesiology
Professor, Medicine
Member, California NanoSystems Institute, Cell & Developmental Biology GPB Home Area, Center for Duchenne Muscular Dystrophy, Genetics & Genomics GPB Home Area, JCCC Signal Transduction and Therapeutics Program Area, Molecular, Cellular & Integrative Physiology GPB Home Area, themes
Faculty, Cardiovascular Research Laboratory, Cardiology
Research Interests
The long term mission of Wang Lab is to understand how stress signaling leads to pathological changes in heart and metabolic system. Using systems genetic approaches and genomic tools, Wang Lab is conducting research in three major areas: 1). Investigating novel lncRNAs and RNA binding proteins in stress-induced pathological remodeling in heart, fat and liver. 2). Discovering novel players in stress-signal transduction. 3). Identifying novel therapeutic targets for heart failure and metabolic disorders.
Biography

Dr. Yibin Wang is currently a Professor of Molecular Medicine in the David Geffen School of Medicine at UCLA. He is the Chair of Cardiovascular Theme at UCLA, the Vice Chair for Research and Director of the Division of Molecular Medicine in the Department of Anesthesiology and Perioperative Medicine. Dr. Wang received his Ph.D. in molecular genetics and cell biology from Baylor College of Medicine and post-doctoral training in neurobiology and molecular cardiology at The Scripps Research Institute and University of California at San Diego. Dr. Wang’s research mainly focuses on genetic and molecular mechanisms of heart failure and metabolic disorders. His lab has made major advances in uncovering stress-signaling mechanisms in the pathogenesis of heart failure, and revealed functional importance amino acids catabolism in heart failure and metabolic disorders. In addition, his lab reported novel regulatory mechanisms in cardiac transcriptome reprogramming involving RNA splicing regulation and non-coding RNA mediated epigenetic modulation. He has published over 163 peer-reviewed manuscripts in high quality scientific journals, including Nature Medicine, Journal of Clinical Investigation, Circulation, Circulation Research, and PNAS. Dr. Wang received an Established Investigator Award from American Heart Association in 2005. He was awarded the title of Chang-Jiang Scholar from Minister of Education of China in 2009, and Chinese National Expert for “Thousand Talent Plan” in 2011. He currently serves in the editorial board of Journal of Biological Chemistry, Circulation Research, and Journal of Molecular and Cellular Cardiology. Dr. Wang is the principal investigator of several NIH grants. He is a member of the leadership committees for AHA and ISHR North American Section. He has served in more than 30 Ph.D. thesis committees, and is currently the course master and Associate Director of the Molecular, Cellular and Integrated Physiology Ph.D. program at UCLA.

Publications
Touma, M.; Kang, X.; Zhao, Y.; Cass, A. A.; Gao, F.; Biniwale, R.; Coppola, G.; Xiao, X.; Reemtsen, B.; Wang, Y. Decoding the Long Noncoding RNA During Cardiac Maturation: A Roadmap for Functional Discovery. Circ Cardiovasc Genet 2016; 9(5): 395-407.
Wang, J. J.; Rau, C.; Avetisyan, R.; Ren, S.; Romay, M. C.; Stolin, G.; Gong, K. W.; Wang, Y.; Lusis, A. J. Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model. PLoS Genet 2016; 12(7): e1006038.
Gao, C.; Wang, Y. Positive Role for a Negative Calcineurin Regulator in Cardiac Hypertrophy. Hypertension 2016; 67(5): 841-2.
Gao, C.; Ren, S.; Lee, J. H.; Qiu, J.; Chapski, D. J.; Rau, C. D.; Zhou, Y.; Abdellatif, M.; Nakano, A.; Vondriska, T. M.; Xiao, X.; Fu, X. D.; Chen, J. N.; Wang, Y. RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure. J Clin Invest 2016; 126(1): 195-206.
Lusis, A. J.; Seldin, M. M.; Allayee, H.; Bennett, B. J.; Civelek, M.; Davis, R. C.; Eskin, E.; Farber, C. R.; Hui, S.; Mehrabian, M.; Norheim, F.; Pan, C.; Parks, B.; Rau, C. D.; Smith, D. J.; Vallim, T.; Wang, Y.; Wang, J. The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits. J Lipid Res 2016; 57(6): 925-42.
Wang, Z.; Zhang, X. J.; Ji, Y. X.; Zhang, P.; Deng, K. Q.; Gong, J.; Ren, S.; Wang, X.; Chen, I.; Wang, H.; Gao, C.; Yokota, T.; Ang, Y. S.; Li, S.; Cass, A.; Vondriska, T. M.; Li, G.; Deb, A.; Srivastava, D.; Yang, H. T.; Xiao, X.; Li, H.; Wang, Y. The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy. Nat Med 2016; 22(10): 1131-1139.
Song, Y.; Zhang, Y.; Jiang, H.; Zhu, Y.; Liu, L.; Feng, W.; Yang, L.; Wang, Y.; Li, M. Activation of Notch3 promotes pulmonary arterial smooth muscle cells proliferation via Hes1/p27Kip1 signaling pathway. FEBS Open Bio 2015; 5: 656-60.
Rau, C. D.; Lusis, A. J.; Wang, Y. Genetics of common forms of heart failure: challenges and potential solutions. Curr Opin Cardiol 2015; 30(3): 222-7.
Rau, C. D.; Parks, B.; Wang, Y.; Eskin, E.; Simecek, P.; Churchill, G. A.; Lusis, A. J. High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. G3 (Bethesda) 2015; 5(10): 2021-6.
Cai, R.; Gu, J.; Sun, H.; Liu, X.; Mei, W.; Qi, Y.; Xue, S.; Ren, S.; Rabinowitz, J. E.; Wang, Y.; Yeh, E. T.; Cheng, J. Induction of SENP1 in myocardium contributes to abnormities of mitochondria and cardiomyopathy. J Mol Cell Cardiol 2015; 79: 115-22.
Feng, J.; Gong, D.; Fu, X.; Wu, T. T.; Wang, J.; Chang, J.; Zhou, J.; Lu, G.; Wang, Y.; Sun, R. M1 of Murine Gamma-Herpesvirus 68 Induces Endoplasmic Reticulum Chaperone Production. Sci Rep 2015; 5: 17228.
Rau, C. D.; Wang, J.; Avetisyan, R.; Romay, M. C.; Martin, L.; Ren, S.; Wang, Y.; Lusis, A. J. Mapping genetic contributions to cardiac pathology induced by Beta-adrenergic stimulation in mice. Circ Cardiovasc Genet 2015; 8(1): 40-9.
Neelankavil, J.; Rau, C. D.; Wang, Y. The Genetic Basis of Coronary Artery Disease and Atrial Fibrillation: A Search for Disease Mechanisms and Therapeutic Targets. J Cardiothorac Vasc Anesth 2015; 29(5): 1328-32.
Ren, S.; Lu, G.; Ota, A.; Zhou, Z. H.; Vondriska, T. M.; Lane, T. F.; Wang, Y. IRE1 phosphatase PP2Ce regulates adaptive ER stress response in the postpartum mammary gland. PLoS One 2014; 9(11): e111606.
Sun, H.; Wang, Y. Interferon regulatory factors in heart: stress response beyond inflammation. Hypertension 2014; 63(4): 663-4.
Lam, M. P.; Wang, D.; Lau, E.; Liem, D. A.; Kim, A. K.; Ng, D. C.; Liang, X.; Bleakley, B. J.; Liu, C.; Tabaraki, J. D.; Cadeiras, M.; Wang, Y.; Deng, M. C.; Ping, P. Protein kinetic signatures of the remodeling heart following isoproterenol stimulation. J Clin Invest 2014; 124(4): 1734-44.
Gao, C.; Wang, Y. Transcriptome complexity in cardiac development and diseases--an expanding universe between genome and phenome. Circ J 2014; 78(5): 1038-47.
Gupta, A.; Rohlfsen, C.; Leppo, M. K.; Chacko, V. P.; Wang, Y.; Steenbergen, C.; Weiss, R. G. Creatine kinase-overexpression improves myocardial energetics, contractile dysfunction and survival in murine doxorubicin cardiotoxicity. PLoS One 2013; 8(10): e74675.
Foster, W. H.; Langenbacher, A.; Gao, C.; Chen, J.; Wang, Y. Nuclear phosphatase PPM1G in cellular survival and neural development. Dev Dyn 2013; 242(9): 1101-9.
Lu, G.; Ota, A.; Ren, S.; Franklin, S.; Rau, C. D.; Ping, P.; Lane, T. F.; Zhou, Z. H.; Reue, K.; Lusis, A. J.; Vondriska, T.; Wang, Y. PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response. Mol Metab 2013; 2(4): 405-16.
Li, J.; Umar, S.; Iorga, A.; Youn, J. Y.; Wang, Y.; Regitz-Zagrosek, V.; Cai, H.; Eghbali, M. Cardiac vulnerability to ischemia/reperfusion injury drastically increases in late pregnancy. Basic Res Cardiol 2012; 107(4): 271.
Gao, C.; Wang, Y. Global impact of RNA splicing on transcriptome remodeling in the heart. J Zhejiang Univ Sci B 2012; 13(8): 603-8.
Ghazalpour, A.; Rau, C. D.; Farber, C. R.; Bennett, B. J.; Orozco, L. D.; van Nas, A.; Pan, C.; Allayee, H.; Beaven, S. W.; Civelek, M.; Davis, R. C.; Drake, T. A.; Friedman, R. A.; Furlotte, N.; Hui, S. T.; Jentsch, J. D.; Kostem, E.; Kang, H. M.; Kang, E. Y.; Joo, J. W.; Korshunov, V. A.; Laughlin, R. E.; Martin, L. J.; Ohmen, J. D.; Parks, B. W.; Pellegrini, M.; Reue, K.; Smith, D. J.; Tetradis, S.; Wang, J.; Wang, Y.; Weiss, J. N.; Kirchgessner, T.; Gargalovic, P. S.; Eskin, E.; Lusis, A. J.; LeBoeuf, R. C. Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mamm Genome 2012; 23(9-10): 680-92.
Sun, H.; Wang, Y. Novel Ser/Thr protein phosphatases in cell death regulation. Physiology (Bethesda) 2012; 27(1): 43-52.
Franklin, S.; Chen, H.; Mitchell-Jordan, S.; Ren, S.; Wang, Y.; Vondriska, T. M. Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth. Mol Cell Proteomics 2012; 11(6): M111 014258.
MacLellan, W. R.; Wang, Y.; Lusis, A. J. Systems-based approaches to cardiovascular disease. Nat Rev Cardiol 2012; 9(3): 172-84.
Foster, W. H.; Tidball, J. G.; Wang, Y. p38gamma activity is required for maintenance of slow skeletal muscle size. Muscle Nerve 2012; 45(2): 266-73.
Sun, H.; Lu, G.; Ren, S.; Chen, J.; Wang, Y. Catabolism of branched-chain amino acids in heart failure: insights from genetic models. Pediatr Cardiol 2011; 32(3): 305-10.
Deng, N.; Zhang, J.; Zong, C.; Wang, Y.; Lu, H.; Yang, P.; Wang, W.; Young, G. W.; Wang, Y.; Korge, P.; Lotz, C.; Doran, P.; Liem, D. A.; Apweiler, R.; Weiss, J. N.; Duan, H.; Ping, P. Phosphoproteome analysis reveals regulatory sites in major pathways of cardiac mitochondria. Mol Cell Proteomics 2011; 10(2): M110 000117.
Marber, M. S.; Rose, B.; Wang, Y. The p38 mitogen-activated protein kinase pathway--a potential target for intervention in infarction, hypertrophy, and heart failure. J Mol Cell Cardiol 2011; 51(4): 485-90.
Streicher, J. M.; Kamei, K.; Ishikawa, T. O.; Herschman, H.; Wang, Y. Compensatory hypertrophy induced by ventricular cardiomyocyte-specific COX-2 expression in mice. J Mol Cell Cardiol 2010; 49(1): 88-94.
Otsuka, M.; Kang, Y. J.; Ren, J.; Jiang, H.; Wang, Y.; Omata, M.; Han, J. Distinct effects of p38alpha deletion in myeloid lineage and gut epithelia in mouse models of inflammatory bowel disease. Gastroenterology 2010; 138(4): 1255-65, 1265 e1-9.
Rose, B. A.; Force, T.; Wang, Y. Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale. Physiol Rev 2010; 90(4): 1507-46.
Ahuja, P.; Zhao, P.; Angelis, E.; Ruan, H.; Korge, P.; Olson, A.; Wang, Y.; Jin, E. S.; Jeffrey, F. M.; Portman, M.; Maclellan, W. R. Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice. J Clin Invest 2010; 120(5): 1494-505.
Paulsson, A. K.; Franklin, S.; Mitchell-Jordan, S. A.; Ren, S.; Wang, Y.; Vondriska, T. M. Post-translational regulation of calsarcin-1 during pressure overload-induced cardiac hypertrophy. J Mol Cell Cardiol 2010; 48(6): 1206-14.
Papanicolaou, K. N.; Streicher, J. M.; Ishikawa, T. O.; Herschman, H.; Wang, Y.; Walsh, K. Preserved heart function and maintained response to cardiac stresses in a genetic model of cardiomyocyte-targeted deficiency of cyclooxygenase-2. J Mol Cell Cardiol 2010; 49(2): 196-209.
Liu, Z.; Fan, H. Y.; Wang, Y.; Richards, J. S. Targeted disruption of Mapk14 (p38MAPKalpha) in granulosa cells and cumulus cells causes cell-specific changes in gene expression profiles that rescue COC expansion and maintain fertility. Mol Endocrinol. 2010; 24(9): 1794-804.
Cross, H. R.; Li, M.; Petrich, B. G.; Murphy, E.; Wang, Y.; Steenbergen, C. Effect of p38 MAP kinases on contractility and ischemic injury in intact heart. Acta Physiol Hung 2009; 96(3): 307-23.
Lu, G.; Sun, H.; Korge, P.; Koehler, C. M.; Weiss, J. N.; Wang, Y. Functional characterization of a mitochondrial Ser/Thr protein phosphatase in cell death regulation. Methods Enzymol 2009; 457: 255-73.
Ruan, H.; Li, J.; Ren, S.; Gao, J.; Li, G.; Kim, R.; Wu, H.; Wang, Y. Inducible and cardiac specific PTEN inactivation protects ischemia/reperfusion injury. J Mol Cell Cardiol 2009; 46(2): 193-200.
Seimon, T. A.; Wang, Y.; Han, S.; Senokuchi, T.; Schrijvers, D. M.; Kuriakose, G.; Tall, A. R.; Tabas, I. A. Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice. J Clin Invest 2009; 119(4): 886-98.
Andersson, K. B.; Finsen, A. V.; Sjaland, C.; Winer, L. H.; Sjaastad, I.; Odegaard, A.; Louch, W. E.; Wang, Y.; Chen, J.; Chien, K. R.; Sejersted, O. M.; Christensen, G. Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models. Cell Calcium 2009; 46(3): 219-25.
Andersson, K. B.; Birkeland, J. A.; Finsen, A. V.; Louch, W. E.; Sjaastad, I.; Wang, Y.; Chen, J.; Molkentin, J. D.; Chien, K. R.; Sejersted, O. M.; Christensen, G. Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene. J Mol Cell Cardiol 2009; 47(2): 180-7.
Lu, G.; Sun, H.; She, P.; Youn, J. Y.; Warburton, S.; Ping, P.; Vondriska, T. M.; Cai, H.; Lynch, C. J.; Wang, Y. Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells. J Clin Invest 2009; 119(6): 1678-87.
Lu, G.; Wang, Y. Functional diversity of mammalian type 2C protein phosphatase isoforms: new tales from an old family. Clin Exp Pharmacol Physiol 2008; 35(2): 107-12.
Streicher, J. M.; Wang, Y. The role of COX-2 in heart pathology. Cardiovasc Hematol Agents Med Chem. 2008; 6(1): 69-79.
Nguyen, C. T.; Lu, Q.; Wang, Y.; Chen, J. N. Zebrafish as a model for cardiovascular development and disease. Drug Discov Today Dis Models 2008; 5(3): 135-140.
Peter, P. S.; Brady, J. E.; Yan, L.; Chen, W.; Engelhardt, S.; Wang, Y.; Sadoshima, J.; Vatner, S. F.; Vatner, D. E. Inhibition of p38 alpha MAPK rescues cardiomyopathy induced by overexpressed beta 2-adrenergic receptor, but not beta 1-adrenergic receptor. J Clin Invest 2007; 117(5): 1335-43.
Ursitti, J. A.; Petrich, B. G.; Lee, P. C.; Resneck, W. G.; Ye, X.; Yang, J.; Randall, W. R.; Bloch, R. J.; Wang, Y. Role of an alternatively spliced form of alphaII-spectrin in localization of connexin 43 in cardiomyocytes and regulation by stress-activated protein kinase. J Mol Cell Cardiol 2007; 42(3): 572-81.
Eghbali, M.; Wang, Y.; Toro, L.; Stefani, E. Heart hypertrophy during pregnancy: a better functioning heart?. Trends Cardiovasc Med 2006; 16(8): 285-91.
Glaser, N. D.; Lukyanenko, Y. O.; Wang, Y.; Wilson, G. M.; Rogers, T. B. JNK activation decreases PP2A regulatory subunit B56alpha expression and mRNA stability and increases AUF1 expression in cardiomyocytes. Am J Physiol Heart Circ Physiol 2006; 291(3): H1183-92.
Liu, J.; Sadoshima, J.; Zhai, P.; Hong, C.; Yang, G.; Chen, W.; Yan, L.; Wang, Y.; Vatner, S. F.; Vatner, D. E. Pressure overload induces greater hypertrophy and mortality in female mice with p38alpha MAPK inhibition. J Mol Cell Cardiol 2006; 41(4): 680-8.
Rehan, V. K.; Wang, Y.; Patel, S.; Santos, J.; Torday, J. S. Rosiglitazone, a peroxisome proliferator-activated receptor-gamma agonist, prevents hyperoxia-induced neonatal rat lung injury in vivo. Pediatr Pulmonol 2006; 41(6): 558-69.
Takimoto, E.; Champion, H. C.; Li, M.; Belardi, D.; Ren, S.; Rodriguez, E. R.; Bedja, D.; Gabrielson, K. L.; Wang, Y.; Kass, D. A. Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy. Nat Med 2005; 11(2): 214-22.
Wang, G.; Liem, D. A.; Vondriska, T. M.; Honda, H. M.; Korge, P.; Pantaleon, D. M.; Qiao, X.; Wang, Y.; Weiss, J. N.; Ping, P. Nitric oxide donors protect murine myocardium against infarction via modulation of mitochondrial permeability transition. Am J Physiol Heart Circ Physiol 2005; 288(3): H1290-5.
Takimoto, E.; Champion, H. C.; Li, M.; Ren, S.; Rodriguez, E. R.; Tavazzi, B.; Lazzarino, G.; Paolocci, N.; Gabrielson, K. L.; Wang, Y.; Kass, D. A. Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load. J Clin Invest 2005; 115(5): 1221-31.
Ren, J.; Zhang, S.; Kovacs, A.; Wang, Y.; Muslin, A. J. Role of p38alpha MAPK in cardiac apoptosis and remodeling after myocardial infarction. J Mol Cell Cardiol 2005; 38(4): 617-23.
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Zheng, M.; Dilly, K.; Dos Santos Cruz, J.; Li, M.; Gu, Y.; Ursitti, J. A.; Chen, J.; Ross, J., Jr.; Chien, K. R.; Lederer, J. W.; Wang, Y. Sarcoplasmic reticulum calcium defect in Ras-induced hypertrophic cardiomyopathy heart. Am J Physiol Heart Circ Physiol 2004; 286(1): H424-33.
Petrich, B. G.; Wang, Y. Stress-activated MAP kinases in cardiac remodeling and heart failure; new insights from transgenic studies. Trends Cardiovasc Med 2004; 14(2): 50-5.
Minamisawa, S.; Wang, Y.; Chen, J.; Ishikawa, Y.; Chien, K. R.; Matsuoka, R. Atrial chamber-specific expression of sarcolipin is regulated during development and hypertrophic remodeling. J Biol Chem. 2003; 278(11): 9570-5..
Christensen, G.; Gruber, P. J.; Wang, Y.; Chien, K. R. Embryonic and neonatal cardiac gene transfer in vivo. Methods Mol Biol. 2003; 219: 169-78.
Wang, Y. Fill a Gab(1) in cardiac hypertrophy signaling: search a missing link between gp130 and ERK5 in hypertrophic remodeling in heart. Circ Res. 2003; 93(3): 186-8..
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Isoda, T.; Paolocci, N.; Haghighi, K.; Wang, C.; Wang, Y.; Georgakopoulos, D.; Servillo, G.; Della Fazia, M. A.; Kranias, E. G.; Depaoli-Roach, A. A.; Sassone-Corsi, P.; Kass, D. A. Novel regulation of cardiac force-frequency relation by CREM (cAMP response element modulator). FASEB J 2003; 17(2): 144-51.
Petrich, B. G.; Molkentin, J. D.; Wang, Y. Temporal activation of c-Jun N-terminal kinase in adult transgenic heart via cre-loxP-mediated DNA recombination. FASEB J 2003; 17(6): 749-51.
Zhang, S.; Weinheimer, C.; Courtois, M.; Kovacs, A.; Zhang, C. E.; Cheng, A. M.; Wang, Y.; Muslin, A. J. The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis. J Clin Invest 2003; 111(6): 833-41.
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Gao Chen, Wang Yibin Untangle a Broken Heart via Janus Kinase 1. Circulation research. 2017; 121(6): 589-590.
Touma Marlin, Kang Xuedong, Gao Fuying, Zhao Yan, Cass Ashley A, Biniwale Reshma, Xiao Xinshu, Eghbali Mansuoreh, Coppola Giovanni, Reemtsen Brian, Wang Yibin Wnt11 regulates cardiac chamber development and disease during perinatal maturation. JCI insight. 2017; 2(17): .
Rosa-Garrido Manuel, Chapski Douglas J, Schmitt Anthony D, Kimball Todd H, Karbassi Elaheh, Monte Emma, Balderas Enrique, Pellegrini Matteo, Shih Tsai-Ting, Soehalim Elizabeth, Liem David A, Ping Peipei, Galjart Niels J, Ren Shuxun, Wang Yibin, Ren Bing, Vondriska Thomas M High Resolution Mapping of Chromatin Conformation in Cardiac Myocytes Reveals Structural Remodeling of the Epigenome in Heart Failure. Circulation. 2017; 23(46): 11175.
Shimizu Hirohito, Langenbacher Adam D, Huang Jie, Wang Kevin, Otto Georg, Geisler Robert, Wang Yibin, Chen Jau-Nian The Calcineurin-FoxO-MuRF1 signaling pathway regulates myofibril integrity in cardiomyocytes. eLife. 2017; 6(6): 589-590.
Touma Marlin, Reemtsen Brian, Halnon Nancy, Alejos Juan, Finn J Paul, Nelson Stanley F, Wang Yibin A Path to Implement Precision Child Health Cardiovascular Medicine. Frontiers in cardiovascular medicine. 2017; 4(4): 36.
Rose Beth A, Yokota Tomohiro, Chintalgattu Vishnu, Ren Shuxun, Iruela-Arispe Luisa, Khakoo Aarif Y, Minamisawa Susumu, Wang Yibin Cardiac Myocyte p38α Kinase Regulates Angiogenesis via Myocyte-Endothelial Cell Cross-talk During Stress-Induced Remodeling in Heart. The Journal of biological chemistry. 2017; 21(4): 817-827.
Gao Chen, Howard-Quijano Kimberly, Rau Christoph, Takamiya Tatsuo, Song Yang, Shivkumar Kalyanam, Wang Yibin, Mahajan Aman Inflammatory and apoptotic remodeling in autonomic nervous system following myocardial infarction. PloS one. 2017; 12(5): e0177750.
Seldin Marcus M, Kim Eric D, Romay Milagros C, Li Shen, Rau Christoph D, Wang Jessica J, Krishnan Karthickeyan Chella, Wang Yibin, Deb Arjun, Lusis Aldons J A systems genetics approach identifies Trp53inp2 as a link between cardiomyocyte glucose utilization and hypertrophic response. American journal of physiology. Heart and circulatory physiology. 2017; 312(4): H728-H741.
Cong Qian, Jia Hao, Li Ping, Qiu Shoutao, Yeh James, Wang Yibin, Zhang Zhen-Lin, Ao Junping, Li Baojie, Liu Huijuan p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner. Scientific reports. 2017; 7(5): 45964.
Pillai Indulekha C L, Li Shen, Romay Milagros, Lam Larry, Lu Yan, Huang Jie, Dillard Nathaniel, Zemanova Marketa, Rubbi Liudmilla, Wang Yibin, Lee Jason, Xia Ming, Liang Owen, Xie Ya-Hong, Pellegrini Matteo, Lusis Aldons J, Deb Arjun Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification. Cell stem cell. 2017; 20(2): 218-232.e5.
Ding Yichen, Lee Juhyun, Ma Jianguo, Sung Kevin, Yokota Tomohiro, Singh Neha, Dooraghi Mojdeh, Abiri Parinaz, Wang Yibin, Kulkarni Rajan P, Nakano Atsushi, Nguyen Thao P, Fei Peng, Hsiai Tzung K Light-sheet fluorescence imaging to localize cardiac lineage and protein distribution. Scientific reports. 2017; 7(3): 42209.
Rau Christoph D, Romay Milagros C, Tuteryan Mary, Wang Jessica J-C, Santolini Marc, Ren Shuxun, Karma Alain, Weiss James N, Wang Yibin, Lusis Aldons J Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice. Cell systems. 2017; 4(1): 121-128.e4.
Sun Haipeng, Wang Yibin Branched chain amino acid metabolic reprogramming in heart failure. Biochimica et biophysica acta. 2016; 1862(12): 2270-2275.
Dong Weibing, Zhou Meiyi, Dong Mei, Pan Bangfen, Liu Yunxia, Shao Jing, Gu Xiaoping, Huang Ying, Li Guangping, Wang Yibin, Sun Haipeng Keto acid metabolites of branched-chain amino acids inhibit oxidative stress-induced necrosis and attenuate myocardial ischemia-reperfusion injury. Journal of molecular and cellular cardiology. 2016; 101(12): 90-98.
Rau, C. D.; Romay, M. C.; Tuteryan, M.; Wang, J. J.; Santolini, M.; Ren, S.; Karma, A.; Weiss, J. N.; Wang, Y.; Lusis, A. J. Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice. Cell Syst 2016; .
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Franklin Sarah, Kimball Todd, Rasmussen Tara L, Rosa-Garrido Manuel, Chen Haodong, Tran Tam, Miller Mickey R, Gray Ricardo, Jiang Shanxi, Ren Shuxun, Wang Yibin, Tucker Haley O, Vondriska Thomas M The chromatin-binding protein Smyd1 restricts adult mammalian heart growth. American journal of physiology. Heart and circulatory physiology. 2016; 311(5): H1234-H1247.
Franklin, S.; Kimball, T.; Rasmussen, T. L.; Rosa-Garrido, M.; Chen, H.; Tran, T.; Miller, M. R.; Gray, R.; Jiang, S.; Ren, S.; Wang, Y.; Tucker, H. O.; Vondriska, T. M. The chromatin-binding protein Smyd1 restricts adult mammalian heart growth. Am J Physiol Heart Circ Physiol 2016; 311(5): H1234-H1247.
Wang, J. J.; Aboulhosn, J. A.; Hofer, I. S.; Mahajan, A.; Wang, Y.; Vondriska, T. M. Operationalizing Precision Cardiovascular Medicine: Three Innovations. Circ Res 2016; 119(9): 984-987.
Touma Marlin, Kang Xuedong, Zhao Yan, Cass Ashley A, Gao Fuying, Biniwale Reshma, Coppola Giovanni, Xiao Xinshu, Reemtsen Brian, Wang Yibin Decoding the Long Noncoding RNA During Cardiac Maturation: A Roadmap for Functional Discovery. Circulation. Cardiovascular genetics. 2016; 9(5): 395-407.
Wang Jessica J, Aboulhosn Jamil A, Hofer Ira S, Mahajan Aman, Wang Yibin, Vondriska Thomas M Operationalizing Precision Cardiovascular Medicine: Three Innovations. Circulation research. 2016; 119(9): 984-987.
Wang Zhihua, Zhang Xiao-Jing, Ji Yan-Xiao, Zhang Peng, Deng Ke-Qiong, Gong Jun, Ren Shuxun, Wang Xinghua, Chen Iris, Wang He, Gao Chen, Yokota Tomohiro, Ang Yen Sin, Li Shen, Cass Ashley, Vondriska Thomas M, Li Guangping, Deb Arjun, Srivastava Deepak, Yang Huang-Tian, Xiao Xinshu, Li Hongliang, Wang Yibin The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy. Nature medicine. 2016; 22(10): 1131-1139.
Rau, C. D.; Gao, C.; Wang, Y. Deconvolution of the Human Endothelial Transcriptome. Cell Syst. 2016; 3(3): 218-220.
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Karbassi Elaheh, Monte Emma, Chapski Douglas J, Lopez Rachel, Rosa Garrido Manuel, Kim Joseph, Wisniewski Nicholas, Rau Christoph D, Wang Jessica J, Weiss James N, Wang Yibin, Lusis Aldons J, Vondriska Thomas M Relationship of disease-associated gene expression to cardiac phenotype is buffered by genetic diversity and chromatin regulation. Physiological genomics. 2016; 48(8): 601-15.
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Monte, E.; Rosa-Garrido, M.; Karbassi, E.; Chen, H.; Lopez, R.; Rau, C. D.; Wang, J.; Nelson, S. F.; Wu, Y.; Stefani, E.; Lusis, A. J.; Wang, Y.; Kurdistani, S. K.; Franklin, S.; Vondriska, T. M. Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION. J Biol Chem 2016; 291(30): 15428-46.
Wang Jessica Jen-Chu, Rau Christoph, Avetisyan Rozeta, Ren Shuxun, Romay Milagros C, Stolin Gabriel, Gong Ke Wei, Wang Yibin, Lusis Aldons J Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model. PLoS genetics. 2016; 12(7): e1006038.
Monte Emma, Rosa-Garrido Manuel, Karbassi Elaheh, Chen Haodong, Lopez Rachel, Rau Christoph D, Wang Jessica, Nelson Stanley F, Wu Yong, Stefani Enrico, Lusis Aldons J, Wang Yibin, Kurdistani Siavash K, Franklin Sarah, Vondriska Thomas M Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION. The Journal of biological chemistry. 2016; 291(30): 15428-46.
Lusis Aldons J, Seldin Marcus M, Allayee Hooman, Bennett Brian J, Civelek Mete, Davis Richard C, Eskin Eleazar, Farber Charles R, Hui Simon, Mehrabian Margarete, Norheim Frode, Pan Calvin, Parks Brian, Rau Christoph D, Smith Desmond J, Vallim Thomas, Wang Yibin, Wang Jessica The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits. Journal of lipid research. 2016; 57(6): 925-42.
Sun, H.; Olson, K. C.; Gao, C.; Prosdocimo, D. A.; Zhou, M.; Wang, Z.; Jeyaraj, D.; Youn, J. Y.; Ren, S.; Liu, Y.; Rau, C. D.; Shah, S.; Ilkayeva, O.; Gui, W. J.; William, N. S.; Wynn, R. M.; Newgard, C. B.; Cai, H.; Xiao, X.; Chuang, D. T.; Schulze, P. C.; Lynch, C.; Jain, M. K.; Wang, Y. Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure. Circulation 2016; 133(21): 2038-49.
Sun Haipeng, Olson Kristine C, Gao Chen, Prosdocimo Domenick A, Zhou Meiyi, Wang Zhihua, Jeyaraj Darwin, Youn Ji-Youn, Ren Shuxun, Liu Yunxia, Rau Christoph D, Shah Svati, Ilkayeva Olga, Gui Wen-Jun, William Noelle S, Wynn R Max, Newgard Christopher B, Cai Hua, Xiao Xinshu, Chuang David T, Schulze Paul Christian, Lynch Christopher, Jain Mukesh K, Wang Yibin Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure. Circulation. 2016; 133(21): 2038-49.
Gao Chen, Wang Yibin Positive Role for a Negative Calcineurin Regulator in Cardiac Hypertrophy. Hypertension (Dallas, Tex. : 1979). 2016; 67(5): 841-2.
Cong, Q.; Jia, H.; Biswas, S.; Li, P.; Qiu, S.; Deng, Q.; Guo, X.; Ma, G.; Ling Chau, J. F.; Wang, Y.; Zhang, Z. L.; Jiang, X.; Liu, H.; Li, B. p38alpha MAPK Regulates Lineage Commitment and OPG Synthesis of Bone Marrow Stromal Cells to Prevent Bone Loss under Physiological and Pathological Conditions. Stem Cell Reports 2016; 6(4): 566-78.
Cong Qian, Jia Hao, Biswas Soma, Li Ping, Qiu Shoutao, Deng Qi, Guo Xizhi, Ma Gang, Ling Chau Jenny Fang, Wang Yibin, Zhang Zhen-Lin, Jiang Xinquan, Liu Huijuan, Li Baojie p38α MAPK Regulates Lineage Commitment and OPG Synthesis of Bone Marrow Stromal Cells to Prevent Bone Loss under Physiological and Pathological Conditions. Stem cell reports. 2016; 6(4): 566-78.
Chen, H.; Orozco, L. D.; Wang, J.; Rau, C. D.; Rubbi, L.; Ren, S.; Wang, Y.; Pellegrini, M.; Lusis, A. J.; Vondriska, T. M. DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States. Circ Res 2016; 118(5): 786-97.
Chen Haodong, Orozco Luz D, Wang Jessica, Rau Christoph D, Rubbi Liudmilla, Ren Shuxun, Wang Yibin, Pellegrini Matteo, Lusis Aldons J, Vondriska Thomas M DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States. Circulation research. 2016; 118(5): 786-97.
Iorga, A.; Li, J.; Sharma, S.; Umar, S.; Bopassa, J. C.; Nadadur, R. D.; Centala, A.; Ren, S.; Saito, T.; Toro, L.; Wang, Y.; Stefani, E.; Eghbali, M. Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy. J Am Heart Assoc 2016; 5(1): .
Yokota, Tomohiro; Wang, Yibin p38 MAP kinases in the heart. Gene 2016; 575(2): 369-376.
Gao Chen, Ren Shuxun, Lee Jae-Hyung, Qiu Jinsong, Chapski Douglas J, Rau Christoph D, Zhou Yu, Abdellatif Maha, Nakano Astushi, Vondriska Thomas M, Xiao Xinshu, Fu Xiang-Dong, Chen Jau-Nian, Wang Yibin RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure. The Journal of clinical investigation. 2016; 126(1): 195-206.
Iorga Andrea, Li Jingyuan, Sharma Salil, Umar Soban, Bopassa Jean C, Nadadur Rangarajan D, Centala Alexander, Ren Shuxun, Saito Tomoaki, Toro Ligia, Wang Yibin, Stefani Enrico, Eghbali Mansoureh Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy. Journal of the American Heart Association. 2016; 5(1): 361-6.
Yokota Tomohiro, Wang Yibin p38 MAP kinases in the heart. Gene. 2016; 575(2 Pt 2): 369-76.
Sun, H.; Wang, Y. The elusive philosopher's stone in young blood. Circ Res 2015; 117(11): 906-8.
Feng Jiaying, Gong Danyang, Fu Xudong, Wu Ting-ting, Wang Jane, Chang Jennifer, Zhou Jingting, Lu Gang, Wang Yibin, Sun Ren M1 of Murine Gamma-Herpesvirus 68 Induces Endoplasmic Reticulum Chaperone Production. Scientific reports. 2015; 5(52): 17228.
Sun Haipeng, Wang Yibin The elusive philosopher's stone in young blood. Circulation research. 2015; 117(11): 906-8.
Cattin, M. E.; Wang, J.; Weldrick, J. J.; Roeske, C. L.; Mak, E.; Thorn, S. L.; DaSilva, J. N.; Wang, Y.; Lusis, A. J.; Burgon, P. G. Deletion of MLIP (Muscle-enriched A-type Lamin-interacting Protein) Leads to Cardiac Hyperactivation of Akt/Mammalian Target of Rapamycin (mTOR) and Impaired Cardiac Adaptation. J Biol Chem 2015; 290(44): 26699-714.
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Neelankavil Jacques, Rau Christoph D, Wang Yibin The Genetic Basis of Coronary Artery Disease and Atrial Fibrillation: A Search for Disease Mechanisms and Therapeutic Targets. Journal of cardiothoracic and vascular anesthesia. 2015; 29(5): 1328-32.
Sun, H.; Gao, C.; Wang, Y. A H(a)rd Way to Adapt in Cardiac Hypertrophy. Circ Res 2015; 117(6): 484-6.
Sun Haipeng, Gao Chen, Wang Yibin A H(a)rd Way to Adapt in Cardiac Hypertrophy. Circulation research. 2015; 117(6): 484-6.
Song Yang, Zhang Yonghong, Jiang Haoxiang, Zhu Yanting, Liu Lu, Feng Wei, Yang Lan, Wang Yibin, Li Manxiang Activation of Notch3 promotes pulmonary arterial smooth muscle cells proliferation via Hes1/p27Kip1 signaling pathway. FEBS open bio. 2015; 5(6): 656-60.
Rau Christoph D, Parks Brian, Wang Yibin, Eskin Eleazar, Simecek Petr, Churchill Gary A, Lusis Aldons J High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. G3 (Bethesda, Md.). 2015; 5(10): 2021-6.
Rau Christoph D, Lusis Aldons J, Wang Yibin Genetics of common forms of heart failure: challenges and potential solutions. Current opinion in cardiology. 2015; 30(3): 222-7.
Deb, A.; Wang, Y. Hypertrophic preconditioning: short-term tricks for long-term gain. Circulation 2015; 131(17): 1468-70.
Deb Arjun, Wang Yibin Hypertrophic preconditioning: short-term tricks for long-term gain. Circulation. 2015; 131(17): 1468-70.
Cai Rong, Gu Jianmin, Sun Haipeng, Liu Xiaobing, Mei Wenhan, Qi Yitao, Xue Song, Ren Shuxun, Rabinowitz Joseph E, Wang Yibin, Yeh Edward T H, Cheng Jinke Induction of SENP1 in myocardium contributes to abnormities of mitochondria and cardiomyopathy. Journal of molecular and cellular cardiology. 2015; 79(1): 115-22.
Rau Christoph D, Wang Jessica, Avetisyan Rozeta, Romay Milagros C, Martin Lisa, Ren Shuxun, Wang Yibin, Lusis Aldons J Mapping genetic contributions to cardiac pathology induced by Beta-adrenergic stimulation in mice. Circulation. Cardiovascular genetics. 2015; 8(1): 40-9.
Wang, Z.; Wang, Y. Dawn of the Epi-LncRNAs: new path from Myheart. Circ Res 2015; 116(2): 235-6.
Wang Zhihua, Wang Yibin Dawn of the Epi-LncRNAs: new path from Myheart. Circulation research. 2015; 116(2): 235-6.
Briot, A.; Jaroszewicz, A.; Warren, C. M.; Lu, J.; Touma, M.; Rudat, C.; Hofmann, J. J.; Airik, R.; Weinmaster, G.; Lyons, K.; Wang, Y.; Kispert, A.; Pellegrini, M.; Iruela-Arispe, M. L. Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Dev Cell 2014; 31(6): 707-21.
Ren Shuxun, Lu Gang, Ota Asuka, Zhou Z Hong, Vondriska Thomas M, Lane Timothy F, Wang Yibin IRE1 phosphatase PP2Ce regulates adaptive ER stress response in the postpartum mammary gland. PloS one. 2014; 9(11): e111606.
Briot Anaïs, Jaroszewicz Artur, Warren Carmen M, Lu Jing, Touma Marlin, Rudat Carsten, Hofmann Jennifer J, Airik Rannar, Weinmaster Gerry, Lyons Karen, Wang Yibin, Kispert Andreas, Pellegrini Matteo, Iruela-Arispe M Luisa Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Developmental cell. 2014; 31(6): 707-21.
Sun Haipeng, Wang Yibin Interferon regulatory factors in heart: stress response beyond inflammation. Hypertension (Dallas, Tex. : 1979). 2014; 63(4): 663-4.
Lam Maggie P Y, Wang Ding, Lau Edward, Liem David A, Kim Allen K, Ng Dominic C M, Liang Xiangbo, Bleakley Brian J, Liu Chenguang, Tabaraki Jason D, Cadeiras Martin, Wang Yibin, Deng Mario C, Ping Peipei Protein kinetic signatures of the remodeling heart following isoproterenol stimulation. The Journal of clinical investigation. 2014; 124(4): 1734-44.
Wang, Y. Blind dates in sciences: dealing with rejection in peer review. Circ Res 2014; 114(6): 944-6.
Xiao, X. G.; Touma, M.; Wang, Y. Decoding the noncoding transcripts in human heart failure. Circulation 2014; 129(9): 958-60.
Wang Yibin Blind dates in sciences: dealing with rejection in peer review. Circulation research. 2014; 114(6): 944-6.
Xiao Xinshu Grace, Touma Marlin, Wang Yibin Decoding the noncoding transcripts in human heart failure. Circulation. 2014; 129(9): 958-60.
Gao Chen, Wang Yibin Transcriptome complexity in cardiac development and diseases--an expanding universe between genome and phenome. Circulation journal : official journal of the Japanese Circulation Society. 2014; 78(5): 1038-47.
Gupta Ashish, Rohlfsen Cory, Leppo Michelle K, Chacko Vadappuram P, Wang Yibin, Steenbergen Charles, Weiss Robert G Creatine kinase-overexpression improves myocardial energetics, contractile dysfunction and survival in murine doxorubicin cardiotoxicity. PloS one. 2013; 8(10): e74675.
Monte Emma, Mouillesseaux Kevin, Chen Haodong, Kimball Todd, Ren Shuxun, Wang Yibin, Chen Jau-Nian, Vondriska Thomas M, Franklin Sarah Systems proteomics of cardiac chromatin identifies nucleolin as a regulator of growth and cellular plasticity in cardiomyocytes. American journal of physiology. Heart and circulatory physiology. 2013; 305(11): H1624-38.
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Foster William H, Langenbacher Adam, Gao Chen, Chen Jaunian, Wang Yibin Nuclear phosphatase PPM1G in cellular survival and neural development. Developmental dynamics : an official publication of the American Association of Anatomists. 2013; 242(9): 1101-9.
Lu Gang, Ota Asuka, Ren Shuxun, Franklin Sarah, Rau Christoph D, Ping Peipei, Lane Timothy F, Zhou Z Hong, Reue Karen, Lusis Aldons J, Vondriska Thomas, Wang Yibin PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response. Molecular metabolism. 2013; 2(4): 405-16.
Force, T.; Wang, Y. Mechanism-based engineering against anthracycline cardiotoxicity. Circulation 2013; 128(2): 98-100.
Force Thomas, Wang Yibin Mechanism-based engineering against anthracycline cardiotoxicity. Circulation. 2013; 128(2): 98-100.
Ahuja, P.; Wanagat, J.; Wang, Z.; Wang, Y.; Liem, D. A.; Ping, P.; Antoshechkin, I. A.; Margulies, K. B.; Maclellan, W. R. Divergent mitochondrial biogenesis responses in human cardiomyopathy. Circulation 2013; 127(19): 1957-67.
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Hofmann Jennifer J, Briot Anais, Enciso Josephine, Zovein Ann C, Ren Shuxun, Zhang Zhen W, Radtke Freddy, Simons Michael, Wang Yibin, Iruela-Arispe M Luisa Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome. Development (Cambridge, England). 2012; 139(23): 4449-60.
Hofmann, J. J.; Briot, A.; Enciso, J.; Zovein, A. C.; Ren, S.; Zhang, Z. W.; Radtke, F.; Simons, M.; Wang, Y.; Iruela-Arispe, M. L. Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome. Development 2012; 139(23): 4449-60.
Hajjar, R. J.; Leri, A.; Wang, Y. BCVS scientific conference 2012 meeting report. Circ Res 2012; 111(9): 1121-4.
Hajjar Roger J, Leri Annarosa, Wang Yibin BCVS scientific conference 2012 meeting report. Circulation research. 2012; 111(9): 1121-4.
Akki, A.; Su, J.; Yano, T.; Gupta, A.; Wang, Y.; Leppo, M. K.; Chacko, V. P.; Steenbergen, C.; Weiss, R. G. Creatine kinase overexpression improves ATP kinetics and contractile function in postischemic myocardium. Am J Physiol Heart Circ Physiol 2012; 303(7): H844-52.
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Weiss James N, Karma Alain, MacLellan W Robb, Deng Mario, Rau Christoph D, Rees Colin M, Wang Jessica, Wisniewski Nicholas, Eskin Eleazar, Horvath Steve, Qu Zhilin, Wang Yibin, Lusis Aldons J "Good enough solutions" and the genetics of complex diseases. Circulation research. 2012; 111(4): 493-504.
Gao Chen, Wang Yibin Global impact of RNA splicing on transcriptome remodeling in the heart. Journal of Zhejiang University. Science. B. 2012; 13(8): 603-8.
Zhou, M.; Lu, G.; Gao, C.; Wang, Y.; Sun, H. Tissue-specific and nutrient regulation of the branched-chain alpha-keto acid dehydrogenase phosphatase, protein phosphatase 2Cm (PP2Cm). J Biol Chem 2012; 287(28): 23397-406.
Zhou Meiyi, Lu Gang, Gao Chen, Wang Yibin, Sun Haipeng Tissue-specific and nutrient regulation of the branched-chain α-keto acid dehydrogenase phosphatase, protein phosphatase 2Cm (PP2Cm). The Journal of biological chemistry. 2012; 287(28): 23397-406.
Sun, H.; Wang, Y. Prostaglandin E2 in remote control of myocardial remodeling. Circulation 2012; 125(23): 2818-20.
Sun Haipeng, Wang Yibin Prostaglandin E2 in remote control of myocardial remodeling. Circulation. 2012; 125(23): 2818-20.
Franklin Sarah, Chen Haodong, Mitchell-Jordan Scherise, Ren Shuxun, Wang Yibin, Vondriska Thomas M Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth. Molecular & cellular proteomics : MCP. 2012; 11(6): M111.014258.
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Huang, Y.; Zhou, M.; Sun, H.; Wang, Y. Branched-chain amino acid metabolism in heart disease: an epiphenomenon or a real culprit?. Cardiovasc Res 2011; 90(2): 220-3.
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