Affiliations

Professor, Psychiatry and Biobehavioral Sciences, Center for Neurobehavioral Genetics, Human Genetics

Member, Bioinformatics GPB Home Area, Brain Research Institute, Genetics & Genomics GPB Home Area, Neuroscience GPB Home Area

The research in Dr. Ophoff’s laboratory focuses on identification of genetic susceptibility of complex traits, in particular neuropsychiatric illnesses such as schizophrenia and bipolar disorder. For this purpose his research includes study of genetic variation at the DNA level, study of gene expression profiles for molecular phenotyping, complemented with efforts to investigate epigenetic variation that may be involved in disease susceptibility. Integration of different types of genomic data into study of the genetic basis of disease is one of the major challenges. Most of his work is funded by the NIH and performed as part of national and international collaborations.

Dr. Roel Ophoff is a professor of Psychiatry and Human Genetics at the UCLA School of Medicine. His research laboratory is located within the Center for Neurobehavioral Genetics and he is member of the Brain Research Institute at UCLA. Dr. Ophoff obtained his PhD in human genetics at the Leiden University in The Netherlands studying the molecular basis of familial migraine. He completed his postdoctoral training in neurogenetics at UC San Francisco. He joined the UCLA faculty in 2002.

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