Lloyd Scott Miller, M.D., Ph.D.

Mailing Address:
200 UCLA Medical Plaza
Los Angeles, CA 90095

Affiliations
Affiliations
Member, Tumor Immunology Program at the Jonsson Comprehensive Cancer Center (JCCC)
Assistant Professor In-Residence, Dermatology
Biography

Dr. Lloyd S. Miller, M.D., Ph.D. is an Assistant Professor and basic science research investigator at the Division of Dermatology at UCLA. Dr. Miller earned his B.A. at the Johns Hopkins University and his M.D. and Ph.D. degrees were earned at the State University of New York Downstate Medical Center. In 2005, he completed his post-doctoral fellowship in the UCLA STAR Program in the laboratory of Robert L. Modlin, M.D. and Genhong Cheng, Ph.D>, and he has stayed on faculty in the Division of Dermatology. Dr. Miller has been awarded an NIH Mentored Clinical Scientist Investigator award to continue his research on mechanisms of cutaneous host defense against bacterial pathogens. In 2009, Dr. Miller was awarded an NIH Research Project Grant Program to study the immune response against Staphylococcus aureus skin infections.

Publications
Muñoz-Planillo Raúl, Franchi Luigi, Miller Lloyd S, Núñez Gabriel A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome. Journal of immunology (Baltimore, Md. : 1950). 2009; 183(6): 3942-8.
Shin Ok S, Miller Lloyd S, Modlin Robert L, Akira Shizuo, Uematsu Satoshi, Hu Linden T Downstream signals for MyD88-mediated phagocytosis of Borrelia burgdorferi can be initiated by TRIF and are dependent on PI3K. Journal of immunology (Baltimore, Md. : 1950). 2009; 183(1): 491-8.
von Köckritz-Blickwede Maren, Rohde Manfred, Oehmcke Sonja, Miller Lloyd S, Cheung Ambrose L, Herwald Heiko, Foster Simon, Medina Eva Immunological mechanisms underlying the genetic predisposition to severe Staphylococcus aureus infection in the mouse model. The American journal of pathology. 2008; 173(6): 1657-68.
Kim Min-Ho, Liu Wei, Borjesson Dori L, Curry Fitz-Roy E, Miller Lloyd S, Cheung Ambrose L, Liu Fu-Tong, Isseroff R Rivkah, Simon Scott I Dynamics of neutrophil infiltration during cutaneous wound healing and infection using fluorescence imaging. The Journal of investigative dermatology. 2008; 128(7): 1812-20.
Miller Lloyd S Toll-like receptors in skin. Advances in dermatology. 2008; 24(7): 71-87.
Miller Lloyd S, Pietras Eric M, Uricchio Lawrence H, Hirano Kathleen, Rao Shyam, Lin Heping, O'Connell Ryan M, Iwakura Yoichiro, Cheung Ambrose L, Cheng Genhong, Modlin Robert L Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo. Journal of immunology (Baltimore, Md. : 1950). 2007; 179(10): 6933-42.
Miller Lloyd S, Modlin Robert L Toll-like receptors in the skin. Seminars in immunopathology. 2007; 29(1): 15-26.
Miller Lloyd S, Modlin Robert L Human keratinocyte Toll-like receptors promote distinct immune responses. The Journal of investigative dermatology. 2007; 127(2): 262-3.
Miller Lloyd S, O'Connell Ryan M, Gutierrez Miguel A, Pietras Eric M, Shahangian Arash, Gross Catherine E, Thirumala Ajaykumar, Cheung Ambrose L, Cheng Genhong, Modlin Robert L MyD88 mediates neutrophil recruitment initiated by IL-1R but not TLR2 activation in immunity against Staphylococcus aureus. Immunity. 2006; 24(1): 79-91.
Miller Lloyd S, Sørensen Ole E, Liu Philip T, Jalian H Ray, Eshtiaghpour Deborah, Behmanesh Behnaz E, Chung Woosin, Starner Timothy D, Kim Jenny, Sieling Peter A, Ganz Tomas, Modlin Robert L TGF-alpha regulates TLR expression and function on epidermal keratinocytes. Journal of immunology (Baltimore, Md. : 1950). 2005; 174(10): 6137-43.
Simm Malgorzata, Miller Lloyd S, Durkin Helen G, Allen Melrose, Chao Wei, Lesner Adam, Potash Mary Jane, Volsky David J Induction of secreted human immunodeficiency virus type 1 (HIV-1) resistance factors in CD4-positive T lymphocytes by attenuated HIV-1 infection. Virology. 2002; 294(1): 1-12.